STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Keywords

Endoplasmic reticulum, Innate immune system, Signal transducing adaptor protein, Sting, Cell biology

References

• Regulation of antiviral innate immune responses by RIG-I family of RNA helicases.Koji Onomoto, Mitsutoshi Yoneyama, Takashi Fujita — 2007
• Fas-Associated Death Domain-Containing Protein-Mediated Antiviral Innate Immune Signaling Involves the Regulation of Irf71Siddharth Balachandran, Thiagarajan Venkataraman, Paul B. Fisher — 2007
• IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblastsSarah M. McWhirter, Katherine A. Fitzgerald, Jacqueline Rosains — 2003
• Recognition of viruses by innate immunityOsamu Takeuchi, Shizuo Akira — 2007
• A FADD-dependent innate immune mechanism in mammalian cellsSiddharth Balachandran, Emmanuel Thomas, Glen N. Barber — 2004
• A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNAKen J. Ishii, Cevayir Coban, Hiroki Kato — 2006
• RalB GTPase-Mediated Activation of the IκB Family Kinase TBK1 Couples Innate Immune Signaling to Tumor Cell SurvivalYuchen Chien, Sungchan Kim, Ron Bumeister — 2006
• The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research.Matthew R. Nelson, Katarzyna Bryc, Karen S. King — 2008
• The exocyst meets the translocon: a regulatory circuit for secretion and protein synthesis?Wei Guo, Peter Novick — 2004
• Genetic analysis of resistance to viral infectionBruce Beutler, Céline Eidenschenk, Karine Crozat — 2007
• Correlation between genetic and geographic structure in Europe.Óscar Lao, Timothy T. Lu, Michael Nothnagel — 2008
• Recognition of cytosolic DNA activates an IRF3-dependent innate immune response.Daniel B. Stetson, Ruslan Medzhitov — 2006
• RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-PhosphatesAndreas Pichlmair, Oliver Schulz, Choon Ping Tan — 2006
• 5'-Triphosphate RNA Is the Ligand for RIG-IVeit Hornung, Jana M. Ellegast, Sarah Kim-Hellmuth — 2006
• VISA is an adapter protein required for virus-triggered IFN-beta signaling.Liang‐Guo Xu, Yan‐Yi Wang, Ke-Jun Han — 2005
• Differential roles of MDA5 and RIG-I helicases in the recognition of RNA virusesHiroki Kato, Osamu Takeuchi, Shintaro Sato — 2006
• A tetrameric complex of membrane proteins in the endoplasmic reticulum.Enno Hartmann, Dirk Görlich, Susanne Kostka — 1993
• The Exocyst Affects Protein Synthesis by Acting on the Translocation Machinery of the Endoplasmic Reticulum*Joshua H. Lipschutz, Vishwanath R. Lingappa, Keith E. Mostov — 2003
• Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses.Kiyohiro Takahasi, Mitsutoshi Yoneyama, Tatsuya Nishihori — 2008
• Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virusEtienne Meylan, Joseph Curran, Kay Hofmann — 2005

Cited by

• Antivirale Immunantwort und Virus-induzierte Apoptose von Insulin-produzierenden Zellen in der Pathogenese des Typ 1 DiabetesStephanie Saskia Kaeser — 2014
• Viral evasion and subversion of pattern-recognition receptor signallingAlbertjan Tollenaar — 2008
• Recognition of viral nucleic acids in innate immunityLuis Sánchez Navarrete — 2010
• TRAF5 Is a Downstream Target of MAVS in Antiviral Innate Immune SignalingМария Андреевна Белопольская — 2010
• Nonstructural NS1 proteins of several mosquito-borne Flavivirus do not inhibit TLR3 signaling.A Proença, F Judas, R Cabral — 2010
• Cell biology and immunology of Listeria monocytogenes infections: novel insightsR. J. Willis — 2011
• Cytosolic DNA sensors regulating type I interferon induction.Borobio Mv — 2011
• Innate immune sensing of cancer: clues from an identified role for type I IFNsPaco Mota — 2012
• Endogenous retroelements and autoimmune diseaseF. Holway — 2012
• The role of innate immune signals in immunity to Brucella abortusDavid A. Morton — 2012
• Type I interferon in neurological disease-the devil from within.Андрей Викторович Фролов — 2013
• Systems biology unravels interferon responses to respiratory virus infections.James L. Rogers, William J. Lamarsh — 2014
• IFITs: Emerging Roles as Key Anti-Viral ProteinsAna Díaz Reina, Ma del Mar San Francisco Roldán — 2014
• Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass CarpOsvaldo Pellettieri — 2015
• Importance of interferon inducible trans-membrane proteins and retinoic acid inducible gene I for influenza virus replication: A reviewMarie-Nöelle De Bechillon — 2015
• Hepatitis C Virus NS4B Can Suppress STING Accumulation To Evade Innate Immune ResponsesByung-Joon Kang, Kang-Ryoung Park — 2015
• Synergy between Hematopoietic and Radioresistant Stromal Cells is Required for Autoimmune Manifestations of DNase II−/− IFNaR−/− MicePeter Bogason, S. Kensen, Hugh T. Miller — 2016
• Type I interferon does not promote susceptibility to foodborne Listeria monocytogenes保 五十嵐, 元 中村, 健 森田 — 2016
• Post-translational regulation of inflammasomesJuan Gabriel Pallarés — 2016
• Post-translational Control of Intracellular Pathogen Sensing PathwaysEduardo Balgueiras, Pere Oliver — 2016

Related papers

• Selective Loss of Responsiveness to Exogenous but Not Endogenous Cyclic-Dinucleotides in Mice Expressing STING-R231HMelissa M. Walker, Soo‐Jin Kim, William J. Crisler — 2020
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• An investigation of the interference effects of a sting support system on the pressure distribution over a body of revolutionHarris M. Schurmeier — 1949
• Spatial evolution of a sting clienteleRobert H. Langworthy, James L. LeBeau — 1992
• Cell dichotomous role of STING in pulmonary hypertensionAnn Pham, Aline C. Oliveira, Chunhua Fu — 2022
• Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T.Daniel R. Beriault, Geoff H. Werstuck — 2013
• Development of VHL-recruiting STING PROTACs that suppress innate immunityZhichuan Zhu, Rebecca L. Johnson, Zhigang Zhang — 2023
• Research Progress on Toll Like Receptors Mediated Signaling Transduction PathwayMA Si-hu — 2014