Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products.
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Summary
The concept of cloning the metagenome to access the collective genomes and the biosynthetic machinery of soil microflora is explored here.
- Type
- article
- Published
- 1998-10-01
- Cited by
- 1,820
- References
- 38
- Access
- Open access
- OpenAlex
- https://openalex.org/W2075716829
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7771854
Keywords
Metagenomics, Natural product, Soil microbiology, Microorganism, Frontier
References
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- Systems analysis of engineered and natural microbial consortia
- Utilizing the Power of Microbial Genetics to Bridge the Gap Between the Promise and the Application of Marine Natural Products
- Screening for new metabolites from marine microorganisms.
- Biodegradation of the cyclic nitramine explosives RDX, HMX, and CL-20
- Metagenomic approaches to exploit the biotechnological potential of the microbial consortia of marine sponges
- [A review on the bioinformatics pipelines for metagenomic research].
- MLTreeMap - accurate Maximum Likelihood placement of environmental DNA sequences into taxonomic and functional reference phylogenies
- Isolation of a Novel Cutinase Homolog with Polyethylene Terephthalate-Degrading Activity from Leaf-Branch Compost by Using a Metagenomic Approach
- High Potential Source for Biomass Degradation Enzyme Discovery and Environmental Aspects Revealed through Metagenomics of Indian Buffalo Rumen
- Improving the genetic representation of rare taxa within complex microbial communities using DNA normalization methods
- Synthetic fermentation of bioactive non-ribosomal peptides without organisms, enzymes or reagents.
- Endospore-enriched sequencing approach reveals unprecedented diversity of Firmicutes in sediments.
- Conjunctival microbiome changes associated with fungal keratitis: metagenomic analysis.
- Genomics and bacterial metabolism.
- A novel function-based screen for detecting RubisCO active clones from metagenomic libraries : elucidating the role of RubisCO associated enzymes.
- Ecological Remediation Using Bacterial, Fungal, and Plant Microcosms: An Effective Solution for Bunker C Crude Oil Contamination in Waterways
- Réponses adaptatives des microorganismes eucaryotes du sol aux pollutions métalliques
- Metagenomic approaches to identify and isolate bioactive natural products from microbiota of marine sponges.
- Functional and metagenomic analysis of the human tongue dorsum using phage display
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