The Landscape of Long Noncoding RNAs in the Human Transcriptome
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Summary
The lncRNA landscape characterized here may shed light on normal biology and cancer pathogenesis and may be valuable for future biomarker development.
- Type
- review
- Published
- 2015-01-19
- Cited by
- 2,527
- References
- 63
- Access
- Open access
- OpenAlex
- https://openalex.org/W2029919331
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:931319
Keywords
Biology, Transcriptome, Computational biology, Gene, Long non-coding RNA
References
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- Molecular signatures database (MSigDB) 3.0
- PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer
- Mutational landscape and significance across 12 major cancer types
- Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer
- Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction
- TP53 genomics predict higher clinical and pathologic tumor response in operable early-stage breast cancer treated with docetaxel-capecitabine ± trastuzumab
- CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model
- The Mutational Landscape of Lethal Castrate Resistant Prostate Cancer
- Recognition of protein coding regions in DNA sequences.
- A draft map of the human proteome
- Genome-wide association study identifies five new breast cancer susceptibility loci
- Pervasive Transcription of the Human Genome Produces Thousands of Previously Unidentified Long Intergenic Noncoding RNAs
Cited by
- lnCaNet: pan-cancer co-expression network for human lncRNA and cancer genes
- Long noncoding RNA LINP1 regulates double strand DNA break repair in triple negative breast cancer
- Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes
- Uncovering the roles of long non-coding RNAs in cancer stem cells
- UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq
- lncFunTK: a toolkit for functional annotation of long noncoding RNAs
- Long noncoding RNA HEGBC promotes tumorigenesis and metastasis of gallbladder cancer via forming a positive feedback loop with IL-11/STAT3 signaling pathway
- Long Non-Coding RNAs as New Master Regulators of Resistance to Systemic Treatments in Breast Cancer
- Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma
- Overexpression of novel lncRNA NLIPMT inhibits metastasis by reducing phosphorylated glycogen synthase kinase 3β in breast cancer
- Multiple Partial Regularized Nonnegative Matrix Factorization for Predicting Ontological Functions of lncRNAs
- Comparative Transcriptomics Analyses across Species, Organs, and Developmental Stages Reveal Functionally Constrained lncRNAs
- Long noncoding RNAs: Lessons from genomic imprinting.
- RNA Biomarkers to Facilitate the Identification of Aggressive Prostate Cancer
- Non-coding RNAs: Epigenetic regulators of bone development and homeostasis
- Functional roles of non-coding Y RNAs
- lncRNAs and microRNAs with a role in cancer development.
- Stressing out over long noncoding RNA
- A co-expression network analysis reveals lncRNA abnormalities in peripheral blood in early-onset schizophrenia.
- Expanding the p53 regulatory network: LncRNAs take up the challenge.
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