Long Non-Coding RNAs as New Master Regulators of Resistance to Systemic Treatments in Breast Cancer
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Summary
It is found that the engagement of lncRNAs in resistance is well described, and that lnc RNAs such as urotelial carcinoma-associated 1 (UCA1) and regulator of reprogramming (ROR) are indeed involved in multiple resistance mechanisms, which offers tantalizing perspectives for wide usage of lNCRNAs as treatment resistance biomarkers.
- Type
- article
- Published
- 2018-09-01
- Cited by
- 49
- References
- 124
- Access
- Open access
- OpenAlex
- https://openalex.org/W30208633
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52197901
Keywords
Phase (matter), Political science, Chemistry
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- Identification of aberrantly methylated differentially expressed genes in breast cancer by integrated bioinformatics analysis
- lncRNA ATXN8OS promotes breast cancer by sequestering miR-204
- Long non‐coding RNA NR2F1‐AS1 promoted proliferation and migration yet suppressed apoptosis of thyroid cancer cells through regulating miRNA‐338‐3p/CCND1 axis
- Crosstalk Between Long Non-coding RNAs, Micro-RNAs and mRNAs: Deciphering Molecular Mechanisms of Master Regulators in Cancer
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- Long non-coding RNA ROR accelerates the progression of breast cancer via promoting stemness in MCF-10A cells
- Long Non-Coding RNA UCA1 Modulates Paclitaxel Resistance in Breast Cancer via miR-613/CDK12 Axis
- Long Non-Coding RNA HOTAIR in Breast Cancer Therapy
- HOX Transcript Antisense RNA HOTAIR Abrogates Vasculogenic Mimicry by Targeting the AngiomiR-204/FAK Axis in Triple Negative Breast Cancer Cells
- Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade.
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- Connecting the Missing Dots: ncRNAs as Critical Regulators of Therapeutic Susceptibility in Breast Cancer