Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

Explore this paper's citation graph

Summary

It is reported here that by acting on NMDA (N-methyl-D-aspartate) receptors on cerebellar cells, glutamate induces the release of a diffusible messenger with strikingly similar properties to EDRF that accounts for the cGMP responses that take place following NMDA receptor activation.

Type
article
Published
1988-11-24
Cited by
2,583
References
21

Keywords

Second messenger system, Glutamate receptor, NMDA receptor, Acetylcholine, Postsynaptic potential

References

Cited by

Related papers