Vascular endothelial cells synthesize nitric oxide from L-arginine

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Summary

It is demonstrated that NO can be synthesized from L-arginine by porcine aortic endothelial cells in culture and the strict substrate specificity of this reaction suggests that L- arginine is the precursor for NO synthesis in vascular endothelium cells.

Type
article
Published
1988-06-16
Cited by
4,982
References
11

Keywords

Nitric oxide, Arginine, Citrulline, Chemistry, Bradykinin

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