Functional analysis of the chromo domain of HP1.

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Summary

It is reported here that point mutations in the HP1 chromo domain abolish the ability of HP1 to promote gene silencing, supporting the view that the chromodomain homology reflects a common mechanistic basis for homeotic and heterochromatic silencing.

Type
article
Published
1995-08-01
Cited by
287
References
40
Access
Open access

Keywords

SAINT, Medical school, Biology, St louis, Library science

References

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