Functional analysis of the chromo domain of HP1.
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Summary
It is reported here that point mutations in the HP1 chromo domain abolish the ability of HP1 to promote gene silencing, supporting the view that the chromodomain homology reflects a common mechanistic basis for homeotic and heterochromatic silencing.
- Type
- article
- Published
- 1995-08-01
- Cited by
- 287
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W160853306
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22640250
Keywords
SAINT, Medical school, Biology, St louis, Library science
References
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- Histones of polytene and nonpolytene nuclei of Drosophila melanogaster.
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- The mouse has a Polycomb-like chromobox gene.
- Phosphorylation of gastrin-17 by epidermal growth factor-stimulated tyrosine kinase
- Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.
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- Determinants of heat shock-induced chromosome puffing.
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- In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster
- Homologous tyrosine phosphorylation sites in transformation-specific gene products of distinct avian sarcoma viruses
- Analysis of P transposable element functions in Drosophila.
- Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.
Cited by
- Defects in Components of the Proteasome Enhance Transcriptional Silencing at Fission Yeast Centromeres and Impair Chromosome Segregation
- Targeted screening for induced mutations
- Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27.
- Epigenetic inheritance of chromatin states mediated by Polycomb and trithorax group proteins in Drosophila.
- Rôle de l'ETP Corto et de la protéine ribosomique RPL12 dans la régulation transcriptionnelle chez Drosophila melanogaster
- upSET, the Drosophila homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks
- Histone modification and the epigenetics of X chromosome inactivation
- Polytene chromosomes, heterochromatin, and position effect variegation.
- Mutations of Pdd1 Chromo- and Chromoshadow Domains Reveal Critical Functions for Each During Development of Tetrahymena thermophila
- Dynamic histone modifications at the promoters of Hox genes in embryonic stem cells
- Chromatin proteins are determinants of centromere function.
- The role of PcG and TrxG proteins in executing epigenetic memory
- The role of HP1α and HP1β in breast cancer progression : a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand
- Three Subfamilies of KRAB Zinc Finger Proteins : A Structural, Functional and Evolutionary Analysis
- ADN ribosomique 5S chez Arabidopsis thaliana : dynamique chromatinienne et ARN polymérase IV
- Versatility of Conviction: Heterochromatin as Both a Repressor and an Activator of Transcription
- Chromatin architecture and the orchestration of gene expression: cell systems to explore epigenetic gene control
- IDENTIFICATION ET CARACTÉRISATION DES CIBLES DE DSP1 CHEZ DROSOPHILA MELANOGASTER.
- Molecular Characterization of the mop2, a Gene Required for Epigenetic Silencing
- High-fidelity mRNA amplification for gene profiling
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