KIR-ligand mismatch in allogeneic hematopoietic stem cell transplantation.
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Summary
It is observed that KIR-ligand mismatch was associated with increased transplantation related mortality (TRM) and decreased overall survival and the presence of alloreactive NK cells can potentially interfere with effective immunity to infections in the early post-transplantation period.
- Type
- review
- Published
- 2005-02-01
- Cited by
- 54
- References
- 18
- OpenAlex
- https://openalex.org/W2019796011
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22411828
Keywords
Transplantation, Haematopoiesis, Immunology, Stem cell, Hematopoietic stem cell transplantation
References
- Determinants of Antileukemia Effects of Allogeneic NK Cells 1
- NK Cell TRAIL Eliminates Immature Dendritic Cells In Vivo and Limits Dendritic Cell Vaccination Efficacy 1
- In search of the 'missing self': MHC molecules and NK cell recognition.
- Alloreactive killer cells: hindrance and help for haematopoietic transplants
- Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor.
- Increased Infection-Related Mortality in KIR-Ligand–Mismatched Unrelated Allogeneic Hematopoietic Stem-Cell Transplantation
- Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect.
- Low incidence of acute graft-versus-host disease, using unrelated HLA-A-, HLA-B-, and HLA-DR-compatible donors and conditioning, including anti-T-cell antibodies.
- The impact of donor KIR and patient HLA-C genotypes on outcome following HLA-identical sibling hematopoietic stem cell transplantation for myeloid leukemia.
- Role of KIR ligand incompatibility in hematopoietic stem cell transplantation using unrelated donors.
- Prevention of graft versus host disease by inactivation of host antigen-presenting cells.
- Cellular and molecular basis of natural killer and natural killer-like activity.
- Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy
- NK cell and DC interactions.
- Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants
- Stimulation of mature unprimed CD8+ T cells by semiprofessional antigen- presenting cells in vivo
- Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors.
- Enhanced cytotoxicity of allogeneic NK cells with killer immunoglobulin-like receptor ligand incompatibility against melanoma and renal cell carcinoma cells.
Cited by
- The Impact of HLA and KIR Ligand Mismatching on Unrelated Allogeneic Hematopoietic Stem Cell Transplantation in Korean Adult Patients
- Human natural killer cell responses to tumour-priming
- Intercellular protein transfer and regulation of inhibitory NK receptor accessibility
- Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity.
- Tumor-Primed NK Cells: Waiting for the Green Light
- Impact of high-resolution matching in allogeneic unrelated donor stem cell transplantation in Switzerland
- Role of killer immunoglobulin-like receptor-ligand interactions in human leukocyte antigen-matched sibling hematopoietic stem cell transplantation.
- Detrimental effect of natural killer cell alloreactivity in T-replete hematopoietic cell transplantation (HCT) for leukemia patients.
- Lentivector-Mediated Transfer of Bmi-1 and Telomerase in Muscle Satellite Cells Yields a Duchenne Myoblast Cell Line with Long-Term Genotypic and Phenotypic Stability
- KIR matching in hematopoietic stem cell transplantation.
- KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation.
- Mapping of susceptibility and protective loci for acute GVHD in unrelated HLA-matched bone marrow transplantation donors and recipients using 155 microsatellite markers on chromosome 22
- The impact of KIR2DS4 alleles and the expression of KIR in the development of acute GVHD after unrelated allogeneic hematopoietic SCT
- Suppression of graft-versus-host disease after adoptive infusion of alloreactive NK cells induced by silencing Ly49C gene in mice.
- The diversity of KIR gene in Chinese Northern Han population and the impact of donor KIR and patient HLA genotypes on outcome following HLA-identical sibling allogeneic hematopoietic stem cell transplantation for hematological malignancy in Chinese people
- Immune modulation by mesenchymal stem cells.
- Killer Ig-like receptor (KIR) compatibility plays a role in the prevalence of acute GVHD in unrelated hematopoietic cell transplants for AML
- G-CSF downregulates natural killer cell-mediated cytotoxicity in donors for hematopoietic SCT
- NK cells expressing inhibitory KIR for non-self-ligands remain tolerant in HLA-matched sibling stem cell transplantation.
- Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT.
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