The impact of donor KIR and patient HLA-C genotypes on outcome following HLA-identical sibling hematopoietic stem cell transplantation for myeloid leukemia.
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Summary
In HLA-matched sibling HSCT for myeloid leukemia, patients homozygous for C2 alleles receiving a graft from a donor carrying the KIR gene KIR2DS2 have a significantly reduced chance of survival.
- Type
- article
- Published
- 2004-02-15
- Cited by
- 202
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W2044835282
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12233970
Keywords
Hematopoietic stem cell transplantation, Immunology, Myeloid, Transplantation, Human leukocyte antigen
References
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- Direct Recognition of Cytomegalovirus by Activating and Inhibitory NK Cell Receptors
- Organization of the leukocyte receptor cluster (LRC) on human Chromosome 19q13.4
- Development of a PCR-SSOP approach capable of defining the natural killer cell inhibitory receptor (KIR) gene sequence repertoires.
- Inhibitory receptors, ITIM sequences and phosphatases.
- Natural killer cell immunoglobulin-like receptor (KIR) locus profiles in African and South Asian populations
- THE DETAILED DISTRIBUTION OF HLA‐A, B, C ANTIGENS IN NORMAL HUMAN ORGANS
- Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor.
- Relevance of KIR gene polymorphisms in bone marrow transplantation outcome.
- Transplants across human leukocyte antigen barriers.
- Reconstitution of NK cell receptor repertoire following HLA-matched hematopoietic cell transplantation.
- Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS
- Human diversity in killer cell inhibitory receptor genes.
- A multi-laboratory characterization of the KIR genotypes of 10th International Histocompatibility Workshop cell lines.
- A structural perspective on MHC class I recognition by killer cell immunoglobulin-like receptors.
- Distribution of natural killer cell immunoglobulin-like receptor sequences in three ethnic groups
Cited by
- The effect of KIR ligand incompatibility on the outcome of unrelated donor transplantation: a report from the center for international blood and marrow transplant research, the European blood and marrow transplant registry, and the Dutch registry.
- Analysis of KIR genes in HLA-identical sibling hematopoietic stem cell transplantation in Thai patients with leukemia.
- Donor selection for patients undergoing allogeneic hematopoietic stem cell transplantation: Assessment of the priorities of Canadian hematopoietic stem cell transplant physicians
- Contribution à l'étude des mécanismes de l'alloréactivité des cellules Natural Killer humaines
- The pattern and functional consequence of Killer Immunoglobulin-like Receptor expression on T cells.
- Expression und Regulation des KIR-Repertoires von humanen Natürlichen Killerzellen
- Rapamycin and MPA, But Not CsA, Impair Human NK Cell Cytotoxicity Due to Differential Effects on NK Cell Phenotype
- Detecting the unusual: natural killer cells.
- Killer cell Immunoglobulin-like Receptor (KIR) polymorphism in Haematopoietic Stem Cell Transplantation (HSCT) : The effect of KIR gene and genotype polymorphism on clinical outcome after HSCT
- Interactions between killer immunoglobulin‐like receptors and their human leucocyte antigen Class I ligands influence the outcome of unrelated haematopoietic stem cell transplantation for thalassaemia: a novel predictive algorithm
- Impact of natural killer cell dose and donor killer‐cell immunoglobulin‐like receptor (KIR) genotype on outcome following human leucocyte antigen‐identical haematopoietic stem cell transplantation
- KIR/HLA‐I mismatching and risk of relapse in paediatric patients undergoing non‐haploidentical allogeneic haematopoietic stem cell transplantation
- Impact of KIR and HLA Genotypes on Outcomes after Reduced-Intensity Conditioning Hematopoietic Cell Transplantation
- The role of KIR-HLA combination in hematopoietic stem cells transplantation
- HLA and KIR gene polymorphism in hematopoietic stem cell transplantation
- KIR2DS1-Positive NK Cells Mediate Alloresponse against the C2 HLA-KIR Ligand Group In Vitro1
- Relevance of C1 and C2 Epitopes for Hemopoietic Stem Cell Transplantation: Role for Sequential Acquisition of HLA-C-Specific Inhibitory Killer Ig-Like Receptor1
- A defined donor activating natural killer cell receptor genotype protects against leukemic relapse after related HLA-identical hematopoietic stem cell transplantation
- Role of HLA in hematopoietic SCT
- Is there an impact of killer cell immunoglobulin-like receptors and KIR-ligand incompatibilities on outcomes after unrelated cord blood stem cell transplantation?
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