Rho GTPases in cell biology
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Summary
Rho GTPases are molecular switches that control a wide variety of signal transduction pathways in all eukaryotic cells and their ability to influence cell polarity, microtubule dynamics, membrane transport pathways and transcription factor activity is probably just as significant.
- Type
- review
- Published
- 2002-12-12
- Cited by
- 4,923
- References
- 81
- OpenAlex
- https://openalex.org/W2019731805
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4332030
Keywords
GTPase, Cell biology, Biology, Signal transduction, Cytoskeleton
References
- Drosophila morphogenesis: movements behind the edge.
- The cell polarity protein ASIP/PAR‐3 directly associates with junctional adhesion molecule (JAM)
- Mechanisms of epithelial fusion and repair
- Rapid Dendritic Remodeling in the Developing Retina: Dependence on Neurotransmission and Reciprocal Regulation by Rac and Rho
- Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo
- Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1
- CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
- Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells
- The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
- Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1
- RHO GTPASES in neuronal morphogenesis
- Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
- Cell motility: can Rho GTPases and microtubules point the way?
- Rho GTPases and cell migration.
- Rho and Rac but not Cdc42 regulate endothelial cell permeability.
- How is actin polymerization nucleated in vivo?
- Rho GTPases Control Polarity, Protrusion, and Adhesion during Cell Movement
- The exocyst is a Ral effector complex
- Guidance of cell migration by the Drosophila PDGF/VEGF receptor.
- PAR‐6 regulates aPKC activity in a novel way and mediates cell‐cell contact‐induced formation of the epithelial junctional complex
Cited by
- Loss of RhoGDI is a novel independent prognostic factor in hepatocellular carcinoma.
- Conserved microtubule–actin interactions in cell movement and morphogenesis
- Mutation of the photoreceptor specific homeodomain gene Pph13 results in defects in phototransduction and rhabdomere morphogenesis
- Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis
- Regulated exocytosis in neuroendocrine cells: a role for subplasmalemmal Cdc42/N-WASP-induced actin filaments.
- Dynamic (re)organization of the podocyte actin cytoskeleton in the nephrotic syndrome
- The Nogo signaling pathway for regeneration block.
- Regulation of actin-based cell migration by cAMP/PKA.
- Apatite-mediated actin dynamics in resorbing osteoclasts.
- G protein control of microtubule assembly.
- Recognition and activation of Rho GTPases by Vav1 and Vav2 guanine nucleotide exchange factors.
- The Rho family of small GTPases: crucial regulators of skeletal myogenesis
- The role of Rho GTPases and SNAREs in mediator release from granulocytes.
- A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts
- Fine Regulation of RhoA and Rock Is Required for Skeletal Muscle Differentiation*
- Comparison of YopE and YopT activities in counteracting host signalling responses to Yersinia pseudotuberculosis infection
- Modeling the cholesteatoma microenvironment: coculture of HaCaT keratinocytes with WS1 fibroblasts induces MMP-2 activation, invasive phenotype, and proteolysis of the extracellular matrix.
- YAP-regulation of dynamic cell behaviour underlying organogenesis
- Impaired tight junction sealing and precocious involution in mammary glands of PKN1 transgenic mice
- Increased Static Pressure Promotes Migration of Vascular Smooth Muscle Cells: Involvement of the Rho-kinase Pathway
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