Rho GTPases and cell migration.
Explore this paper's citation graph
Summary
New molecular links between Rho family proteins and the actin cytoskeleton are revealed, showing that they act to regulate actin polymerization, depolymerization and the activity of actin-associated myosins.
- Type
- review
- Published
- 2001-08-01
- Cited by
- 1,239
- References
- 145
- OpenAlex
- https://openalex.org/W1910650341
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27355103
Keywords
Biology, Cell biology, Cell migration, GTPase, Cytoskeleton
References
- Membrane association and targeting of prenylated Ras-like GTPases.
- Cdc42-interacting Protein 4 Mediates Binding of the Wiskott-Aldrich Syndrome Protein to Microtubules*
- A Novel C3-like ADP-ribosyltransferase fromStaphylococcus aureus Modifying RhoE and Rnd3*
- Rnd proteins: a new family of Rho-related proteins that interfere with the assembly of filamentous actin structures and cell adhesion.
- Purification of recombinant Rho/Rac/G25K from Escherichia coli.
- Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics
- The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation.
- Cofilin/ADF is required for cell motility during Drosophila ovary development and oogenesis
- EPS8 and E3B1 transduce signals from Ras to Rac
- Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading
- Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases
- Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1
- CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
- Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts
- Stress fibres take shape
- IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling
- Rho Proteins: Linking Signaling with Membrane Trafficking
- Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration
- Cell polarity: new PARtners for Cdc42 and Rac
- Regulation of matrix metalloproteinase expression in tumor invasion
Cited by
- The role and regulation of PAK isoforms in cancer cell migration
- Actin, microtubules and focal adhesion dynamics during cell migration.
- Conserved microtubule–actin interactions in cell movement and morphogenesis
- Statin decreases endothelial microparticle release from human coronary artery endothelial cells: implication for the Rho-kinase pathway.
- A general approach for chemical labeling and rapid, spatially controlled protein inactivation.
- Regulation of actin-based cell migration by cAMP/PKA.
- G protein control of microtubule assembly.
- NELIN, a new F-actin associated protein, stimulates HeLa cell migration and adhesion.
- Modeling the cholesteatoma microenvironment: coculture of HaCaT keratinocytes with WS1 fibroblasts induces MMP-2 activation, invasive phenotype, and proteolysis of the extracellular matrix.
- Mathematical Model for Spatial Segregation of the Rho-Family GTPases Based on Inhibitory Crosstalk
- Small GTP-binding proteins and their regulators in cardiac hypertrophy.
- The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.
- Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression
- 非小细胞肺癌中PRL-3与RhoC的表达及相关性意义
- Interplay between β1-Integrin and Rho Signaling Regulates Differential Scattering and Motility of Pancreatic Cancer Cells by Snail and Slug Proteins*
- FRET imaging and statistical signal processing reveal positive and negative feedback loops regulating the morphology of randomly migrating HT-1080 cells
- Irradiation‐tolerant lung cancer cells acquire invasive ability dependent on dephosphorylation of the myosin regulatory light chain
- Multi-level control of actin dynamics by protein kinase D.
- Gamma Interferon-Induced Guanylate Binding Protein 1 Is a Novel Actin Cytoskeleton Remodeling Factor
- ERM proteins in cancer progression
Related papers
- The Influence of PKA and RhoA on Migration of Gastric Cancer Cells
- Comparison between fibroblast wound healing and cell random migration assays in vitro.
- Comparative functional analysis of the Rac GTPases
- Advances in mechanisms of cancer cell motility and migration
- On how Rac controls hematopoietic stem cell activity
- Rac GTPases in Human Diseases
- Rac GTPases in Human Diseases
- Rho family GTPases.
- Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders