Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
Explore this paper's citation graph
Summary
The focus of this review is on the early steps in mammalian BER for oxidized damage, which are sometimes covalently modified which may affect activity and complex formation.
- Type
- review
- Published
- 2008-01-01
- Cited by
- 663
- References
- 190
- Access
- Open access
- OpenAlex
- https://openalex.org/W2010339813
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12358756
Keywords
DNA glycosylase, Biology, Base excision repair, AP endonuclease, DNA repair
References
- Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
- Structural characterization of the Fpg family of DNA glycosylases.
- XRCC1 co-localizes and physically interacts with PCNA.
- Flap endonuclease 1: a central component of DNA metabolism.
- DNA repair: from molecular mechanism to human disease.
- Regulation of repair of alkylation damage in mammalian genomes.
- DNA Repair and Mutagenesis
- Choreography of oxidative damage repair in mammalian genomes.
- 8-Hydroxydeoxyguanosine and 8-hydroxyguanine as biomarkers of oxidative DNA damage.
- Predicting Protein Disorder for N-, C-, and Internal Regions.
- Molecular mechanism of PCNA-dependent base excision repair.
- Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells.
- Reconstitution of DNA base excision‐repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
- A new endonuclease from Escherichia coli acting at apurinic sites in DNA.
- Passing the baton in base excision repair
- Functional sites of interaction between release factor RF1 and the ribosome
- Base excision repair of mitochondrial DNA damage in mammalian cells.
- Base excision repair in nuclear and mitochondrial DNA.
- Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress.
- The Saccharomyces cerevisiae Homologues of Endonuclease III from Escherichia coli, Ntg1 and Ntg2, Are Both Required for Efficient Repair of Spontaneous and Induced Oxidative DNA Damage in Yeast
Cited by
- Exploring the Early Effects of AP Endonuclease 1 Knockdown in Zebrafish Embryogenesis
- Induction of adaptive response and enhancement of PC12 cell tolerance by lipopolysaccharide primarily through the upregulation of glutathione S-transferase A3 via Nrf2 activation.
- Assaying break and nick-induced homologous recombination in mammalian cells using the DR-GFP reporter and Cas9 nucleases
- Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe
- APOPTOSIS INDUCED BY PERSISTENT SINGLE-STRAND BREAKS IN THE MITOCHONDRIAL GENOME: CRITICAL ROLE OF EXOG (5’ EXO/ENDONUCLEASE) IN THEIR REPAIR
- Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli
- Hippocampal adult neurogenesis is maintained by Neil3-dependent repair of oxidative DNA lesions in neural progenitor cells.
- Repair of Oxidative DNA Base Damage in the Host Genome Influences the HIV Integration Site Sequence Preference
- Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A
- OXIDATIVE DAMAGE TO DNA IN ALZHEIMER'S DISEASE
- Poly(ADP-ribose) protects vascular smooth muscle cells from oxidative DNA damage
- Exposure to polycyclic aromatic hydrocarbons: bulky DNA adducts and cellular responses.
- Interstrand Crosslinks - Induction and repair
- Mécanismes impliqués dans la formation des anomalies chromosomiques lors de la meiose en absence de brca2 chez la plante arabidopsis thaliana
- Mouse Embryonic Stem Cells
- Fréquence et distribution des dimères cyclobutyliques de pyrimidines suite à une exposition aux UV et évaluation de l’effet protecteur de l’acide sulfonique 2-phénylbenzymidazole-5
- Learning tasks as a possible treatment for DNA lesions induced by oxidative stress in hippocampal neurons
- The role of GAPDH in maintaining the functional state of the DNA repair enzyme APE1
- Pathogenicity, functional significance and clinical phenotype of mismatch repair gene MSH2 variants found in cancer patients
- Molecular Determinants of Radiation Response
Related papers
- Bcl2 Inhibits Abasic Site Repair by Down-regulating APE1 Endonuclease Activity*
- Complementary Functions of Plant AP Endonucleases and AP Lyases during DNA Repair of Abasic Sites Arising from C:G Base Pairs
- Nonenzymatic release of N7-methylguanine channels repair of abasic sites into an AP endonuclease-independent pathway in Arabidopsis
- XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein–protein interactions
- AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate.
- Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System
- Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA
- DNA polymerase beta and mammalian base excision repair.
- Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex*