Cellular mechanisms and physiological consequences of redox-dependent signalling
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Summary
The sources of ROS within cells and what is known regarding how intracellular oxidant levels are regulated are discussed, with the recent observations that reduction–oxidation (redox)-dependent regulation has a crucial role in an ever-widening range of biological activities.
- Type
- review
- Published
- 2014-05-23
- Cited by
- 1,925
- References
- 127
- OpenAlex
- https://openalex.org/W2007636933
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7335256
Keywords
Reactive oxygen species, Cell biology, Signal transduction, Intracellular, Cell fate determination
References
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- Forkhead Box O as a Sensor, Mediator, and Regulator of Redox Signaling
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- Redox regulation and pro-oxidant reactions in the physiology of circadian systems.
- Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling
- Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathway
- The Tumorigenic Roles of the Cellular REDOX Regulatory Systems
- Global transcriptome analyses provide evidence that chloroplast redox state contributes to intracellular as well as long-distance signalling in response to stress and acclimation in Arabidopsis
- Oleanolic acid derivative SZC014 inhibit cell proliferation and induce apoptosis of human breast cancer cells in a ROS-dependent way.
- Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria.
- Baicalin Ameliorates Experimental Liver Cholestasis in Mice by Modulation of Oxidative Stress, Inflammation, and NRF2 Transcription Factor
- Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes
- Redox cycling induces spermptosis and necrosis in stallion spermatozoa while the hydroxyl radical (OH•) only induces spermptosis
- Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling?
- KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease
- Metabolic regulation of NLRP3
- Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis.
- How the phagocyte NADPH oxidase regulates innate immunity
- Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds.
- Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease
- Piperlongumine Induces Cell Cycle Arrest via Reactive Oxygen Species Accumulation and IKKβ Suppression in Human Breast Cancer Cells
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