Modulation of oxidative stress as an anticancer strategy
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Summary
The controversial role of ROS in tumour development and in responses to anticancer therapies is addressed, and the idea that targeting the antioxidant capacity of tumour cells can have a positive therapeutic impact is elaborate.
- Type
- review
- Published
- 2013-11-29
- Cited by
- 3,272
- References
- 240
- OpenAlex
- https://openalex.org/W1969524738
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20604657
Keywords
Oxidative stress, Carcinogenesis, Reactive oxygen species, DNA damage, Cell biology
References
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Cited by
- Non-Inflammasome Forming NLRs in Inflammation and Tumorigenesis
- Oxidants and Antioxidants in Metabolic Syndrome and Cancer
- Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells
- Nanomedicine in the ROS-Mediated Pathophysiology: Applications and Clinical Advances
- Glutaminolysis as a target for cancer therapy
- The Tumorigenic Roles of the Cellular REDOX Regulatory Systems
- Reactive Oxygen Species and Targeted Therapy for Pancreatic Cancer
- ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia
- Phytomedicine-Modulating oxidative stress and the tumor microenvironment for cancer therapy.
- Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling.
- Dissecting the 17β‐estradiol pathways necessary for neuroglobin anti‐apoptotic activity in breast cancer
- A promising redox cycle‐based strategy for designing a catechol‐type diphenylbutadiene as a potent prooxidative anti‐melanoma agent
- The CHD6 chromatin remodeler is an oxidative DNA damage response factor
- Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity
- Ageing and Osteoarthritis.
- The Yin and Yang of cancer genes.
- Cooperative coordination-mediated multi-component self-assembly of “all-in-one” nanospike theranostic nano-platform for MRI-guided synergistic therapy against breast cancer
- Benzyl Isothiocyanate as an Adjuvant Chemotherapy Option for Head and Neck Squamous Cell Carcinoma
- Expression of reactive oxygen species-related proteins in metastatic breast cancer is dependent on the metastatic site.
- Studies on Periodontal Disease
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