Ceramides as modulators of cellular and whole-body metabolism.

Keywords

Ceramide, Sphingolipid, Anabolism, Catabolism, Intracellular

References

• Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.Marta Salinas, Raquel López‐Valdaliso, Daniel Martı́n — 2000
• Is Autophagy the Key Mechanism by Which the Sphingolipid Rheostat Controls the Cell Fate Decision?Jeffrey Luckins, Indra Abeysekera, Tong-Gunn Chew — 2007
• Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin ResistanceGabriel Luiz Machado — 2007
• The many ways to regulate glucose transporter 4.Amira Klip — 2009
• Involvement of mitochondrial contact sites in the subcellular compartmentalization of phospholipid biosynthetic enzymes.Dominique Ardail, F. Gasnier, F. Lermé — 1993
• Ceramide activates heterotrimeric protein phosphatase 2A.Rick T. Dobrowsky, Craig Kamibayashi, Marc C. Mumby — 1993
• LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice.Sandra A. Schreyer, Cynthia M. Vick, Ted Lystig — 2002
• Hypothalamic insulin signaling is required for inhibition of glucose productionSilvana Obici, Bei B. Zhang, George B. Karkanias — 2002
• Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivityMette Skovbro, Marcin Baranowski, Camilla Skov-Jensen — 2008
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• Ceramide down‐regulates System A amino acid transport and protein synthesis in rat skeletal muscle cellsRussell Hyde, Éric Hajduch, Darren Powell — 2005
• Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.Wissal El-Assaad, Jean Buteau, Marie‐Line Peyot — 2003
• Ceramide: a common pathway for atherosclerosis?Jean Bismuth, Peter H. Lin, Qizhi Yao — 2008
• Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.Gökhan S. Hotamışlıgil, Peter Arner, J F — 1995
• Targeting of PKCzeta and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide.Éric Hajduch, Sophie Turban, Xavier Le Lièpvre — 2008
• Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fractionHiroshi Shimeno, Shinji Soeda, Masahiko Sakamoto — 1998
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Cited by

• Cardiac Metabolism in Heart Failure - Implications beyond ATP productionEleeja Shrestha, Sajjad Ahmad, Walter Johnson — 2013
• SphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes[S]Голдин Владислав Иванович, Трошина Татьяна Игоревна — 2015
• De Novo Lipogenesis Products and Endogenous LipokinesM. Agrifoglio — 2016
• Evolution of Membrane Bound Proteins and their Ligands : The Melanocortin (MC) Receptor Inverse Agonists AgRP2, ASIP2, Drug/Metabolite Transporters, and SPNS1Åke Västermark — 2012
• Fatty acids, monocytes and ageingChathyan Pararasa — 2013
• The Role of Receptors for Advanced Glycation End-Products (RAGE) and Ceramide in Cardiovascular DiseaseMichael B. Nelson — 2015
• Modulation of skeletal muscle insulin sensitivity and SNAT2 amino acid transporter expression by fatty acid availabilityFrancesca Nardi — 2015
• Lipid-mediated muscle insulin resistance: different fat, different pathways?Olesja Ritter, Tomáš Jeleník, Michael Roden — 2015
• Safety and risk assessment of ceramide 3 in cosmetic products.Seul Min Choi, Byung‐Mu Lee — 2015
• Glucose and lipid metabolism in human skeletal musclePaulina Skrobuk — 2012
• The Role of Ceramides in Mediating Endotoxin-Induced Mitochondrial DisruptionMelissa E. Hansen — 2014
• The effect of short‐term overfeeding on serum lipids in healthy humansLeonie K. Heilbronn, Adelle C.F. Coster, Lesley V. Campbell — 2013
• Effect of pioglitazone on plasma ceramides in adults with metabolic syndromeJeremy Warshauer, Ximena López, Ruth Gordillo — 2015
• Dihydroceramides: From Bit Players to Lead Actors*Monowarul Mobin Siddique, Ying Li, Bhagirath Chaurasia — 2015
• Insulin resistance in clinical and experimental alcoholic liver diseaseRotonya M. Carr, Jason Correnti — 2015
• Role of acid sphingomyelinase bioactivity in human CD4+ T-cell activation and immune responsesAiping Bai, E. Kokkotou, Yi Zheng — 2015
• TOR complex 2 regulates plasma membrane homeostasisDoris Berchtold — 2012
• Transcriptional and Post-transcriptional Regulation of Hepcidin and Iron Metabolism by Lipid Signaling in the LiverSizhao Lu — 2015
• Functional inhibitors of acid sphingomyelinase (FIASMAs).Johannes Kornhuber, Philipp Tripal, Erich Gulbins — 2013
• Microsomal Triglyceride Transfer Protein Transfers and Determines Plasma Concentrations of Ceramide and Sphingomyelin but Not Glycosylceramide*Jahangir Iqbal, Meghan T. Walsh, Samar M. Hammad — 2015

Related papers

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• Ceramide Transfer Protein and CancerLuana Scheffer, Pralhada Rao Raghavendra, Jingjing Ma — 2011
• Ceramide synthases as potential targets for therapeutic intervention in human diseases.Joo‐Won Park, Woo‐Jae Park, Anthony H. Futerman — 2014
• Expression of Ceramide Synthases in Mice and Their Roles in Regulating Acyl-Chain Sphingolipids: A Framework for Baseline Levels and Future Implications in Aging and DiseaseWhitney J. Richardson, Sophia B. Humphrey, Sophia M. Sears — 2023
• High fat diet induces ceramide and sphingomyelin formation in rat’s liver nucleiGrzegorz Chocian, Adrian Chabowski, Małgorzata Żendzian‐Piotrowska — 2010
• Ceramide function in the brain: when a slight tilt is enoughChiara Mencarelli, Pilar Martínez‐Martínez — 2012
• Ceramide synthase.Elaine Wang, Alfred H. Merrill — 2000
• Measurement of ceramide and sphingolipid metabolism in tumors: potential modulation of chemotherapy.David E. Modrak — 2005