Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance

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Summary

It is shown that C3H/HeJ mice, which have a loss-of-function mutation in TLR4, are protected against the development of diet-induced obesity and a potential target for the therapy of these highly prevalent medical conditions.

Type
article
Published
2007-08-01
Cited by
837
References
51
Access
Open access

Keywords

Political science

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