SYFPEITHI: database for MHC ligands and peptide motifs
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Summary
The first version of the major histocompatibility complex (MHC) databank SYFPEITHI: database for MHC ligands and peptide motifs, is now available to the general public.
- Type
- review
- Published
- 1999-10-30
- Cited by
- 2,504
- References
- 22
- OpenAlex
- https://openalex.org/W1994048581
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1407069
Keywords
Major histocompatibility complex, Biology, MHC class II, Epitope, Computational biology
References
- MHC Ligands and Peptide Motifs
- Molecular approaches to the control of infectious diseases
- Functional analysis of DR17(DR3)-restricted mycobacterial T cell epitopes reveals DR17-binding motif and enables the design of allele-specific competitor peptides.
- HLA-DR3 molecules can bind peptides carrying two alternative specific submotifs.
- Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
- Peptide motif of HLA-B*1510
- HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides
- A comprehensive set of sequence analysis programs for the VAX
- A DR17‐restricted T cell epitope from a secreted Mycobacterium tuberculosis antigen only binds to DR17 molecules at neutral pH
- Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning
- Prediction of HIV Peptide Epitopes by a Novel Algorithm
- Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant.
- Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles
- A computer program for predicting possible cytotoxic T lymphocyte epitopes based on HLA class I peptide-binding motifs.
- Two novel T cell epitope prediction algorithms based on MHC-binding motifs; comparison of predicted and published epitopes from Mycobacterium tuberculosis and HIV protein sequences.
- Natural peptide ligand motifs of two HLA molecules associated with myasthenia gravis.
- MHCPEP, a database of MHC-binding peptides: update 1996
- Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains.
- A computer program: As a specific example of the broadening use of computers in chemistry covered in the previous News Focus by C&EN's Joe Haggin, three chemists discuss in detail one system for computer- assisted organic synthesis.
- MHCPEP, a database of MHC-binding peptides: update 1997
Cited by
- Project 1: “Towards a prophylactic Epstein Barr Virus (EBV) vaccine to prevent EBV -associated malignancies and infectious mononucleosis” and project 2: “Analysing the transcriptional response to histone deacetylase inhibitors treatment in normal and cancer cell lines”
- Multi-Scale Modeling of Antigen Presentation With Applications to Tuberculosis.
- Examination of possible structural constraints of MHC‐binding peptides by assessment of their native structure within their source proteins
- Harnessing the cellular immune system to the gene-prediction cart.
- Peptide libraries for T cell epitope screening and characterization.
- Are there HLA combinations typical supporting for or making resistant against aggressive and/or chronic periodontitis?
- The role of idiotype-specific immunity in antigen receptor diversity
- Novel strategy for identification of candidate cytotoxic T-cell epitopes from human preproinsulin.
- Heterozygote advantage fails to explain the high degree of polymorphism of the MHC
- Cleaving proteins for the immune system.
- T-cell epitope peptide vaccines
- Identification and characterization of epitopes of the receptor for hyaluronic acid-mediated motility (RHAMM/CD168) recognized by CD8+ T cells of HLA-A2-positive patients with acute myeloid leukemia.
- Design of enhanced agonists through the use of a new virtual screening method: Application to peptides that bind class I major histocompatibility complex (MHC) molecules
- Learning MHC I - peptide binding
- Prediction and Molecular Modeling of T-cell Epitopes Derived from Placental Alkaline Phosphatase for use in Cancer Immunotherapy
- CD8+ T-Cell Responses Identify β-Cell Autoimmunity in Human Type 1 Diabetes
- In silico prediction of peptide-MHC binding affinity using SVRMHC.
- The TAG Family of Cancer/Testis Antigens is Widely Expressed in a Variety of Malignancies and Gives Rise to HLA-A2–Restricted Epitopes
- MHC presentation via autophagy and how viruses escape from it
- Computer aided selection of candidate vaccine antigens
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