Signal transduction from multiple Ras effectors.
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- Type
- review
- Published
- 1997-02-01
- Cited by
- 321
- References
- 49
- OpenAlex
- https://openalex.org/W1988409513
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9628181
Keywords
Biology, Signal transduction, Effector, Cell biology, Kinase
References
- RapV12 antagonizes Ras‐dependent activation of ERK1 and ERK2 by LPA and EGF in Rat‐1 fibroblasts.
- Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta.
- Ral‐GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation.
- Ras target proteins in eukaryotic cells
- Evidence for the in vitro and in vivo interaction of Ras with protein kinase C zeta.
- Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains
- Phosphatidylinositol-3-OH kinase direct target of Ras
- Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target.
- A branched signaling pathway for nerve growth factor is revealed by Src-, Ras-, and Raf-mediated gene inductions
- Characterization of a guanine nucleotide dissociation stimulator for a ras‐related GTPase.
- Activation of phosphoinositide 3‐kinase by interaction with Ras and by point mutation.
- Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
- The ras oncogene--an important regulatory element in lower eucaryotic organisms
- ralGDS family members interact with the effector loop of ras p21
- Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins.
- Ras‐related proteins in signal transduction and growth control
- Raf meets Ras: completing the framework of a signal transduction pathway.
- A Constitutive Effector Region on the C-terminal Side of Switch I of the Ras Protein (*)
- Proteins regulating Ras and its relatives
- Direct Interaction between Ras and the Kinase Domain of Mitogen-activated Protein Kinase Kinase Kinase (MEKK1) (*)
Cited by
- G proteins, effectors and GAPs: structure and mechanism.
- Constitutive active p21ras enhances primary T cell responsiveness to Ca2+ signals without interfering with the induction of clonal anergy
- Synergistic cytotoxic effects in myeloid leukemia cells upon cotreatment with farnesyltransferase and geranylgeranyl transferase-I inhibitors
- Regulation of the Ras-MAPK pathway at the level of Ras and Raf.
- Identification of Essential Interacting Elements in K-Ras/Calmodulin Binding and Its Role in K-Ras Localization*
- Dissecting the telomere-independent pathways underlying human cellular senescence
- Étude des voies de signalisation impliquées dans le contrôle de l’expression de SMN dans des modèles murins d’Amyotrophie Spinale Infantile
- K-ras expression--marker of dysplasia and cancer.
- RAS pathways to cell cycle control and cell transformation.
- Signaling networks controlling mucin production in response to Gram-positive and Gram-negative bacteria
- Targeting the Ras signaling pathway: a rational, mechanism-based treatment for hematologic malignancies?
- Tropomyosin as a regulator of cancer cell transformation.
- Identification of the Rassf3 gene as a potential tumor suppressor responsible for the resistance to mammary tumor development in MMTV/neu transgenic mice
- Characterisation of high and low avidity peptide specific CD8+ T cells using immunologic, transcriptomic and proteomic tools
- Death Pathways Triggered by Activated Ras in Cancer Cells
- K-Ras-mediated increase in cyclooxygenase 2 mRNA stability involves activation of the protein kinase B1.
- Anti-tumor effect of bisphosphonate (YM529) on non-small cell lung cancer cell lines
- Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases
- Exploring environmental causes of altered ras effects: Fragmentation plus integration?
- Isthmus organizer for mesencephalon and metencephalon
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