DNA methylation: roles in mammalian development
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Summary
Key concepts in the function of DNA methylation in mammals are discussed, stemming from more than two decades of research, including many recent studies that have elucidated when and whereDNA methylation has a regulatory role in the genome.
- Type
- review
- Published
- 2013-02-12
- Cited by
- 2,892
- References
- 211
- OpenAlex
- https://openalex.org/W1987557775
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14253509
Keywords
Biology, DNA methylation, Epigenomics, Epigenetics, Epigenetics of physical exercise
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- Role of the Keap1-Nrf2 pathway in cancer.
- Evidence for a Functional Link between Chromosomal Breakpoints and Aberrant DNA Methylation in Cancer
- Overlapping DNA Methylation Dynamics in Mouse Intestinal Cell Differentiation and Early Stages of Malignant Progression
- Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer
- Cell cycle arrest induced by inhibitors of epigenetic modifications in maize (Zea mays) seedling leaves: characterization of the process and possible mechanisms involved.
- The Epigenetic Paradox of Pluripotent ES Cells.
- DNA methyltransferases and their roles in tumorigenesis
- Erasure of Tet-Oxidized 5-Methylcytosine by a SRAP Nuclease.
- Genome-wide analysis of DNA methylation in five tissues of sika deer (Cervus nippon).
- The IDH1 Mutation-Induced Oncometabolite, 2-Hydroxyglutarate, May Affect DNA Methylation and Expression of PD-L1 in Gliomas
- DNA Methylation Regulates Corneal Epithelial Wound Healing by Targeting miR-200a and CDKN2B.
- New tools for 'ZEBRA-FISHING'.
- The role of macrophages in the innate immune response to Streptococcus pneumoniae and Staphylococcus aureus: mechanisms and contrasts.
- Transcriptional and Epigenetic Regulation of Epithelial-Mesenchymal Transition
- Genome-Wide Studies of Transcriptional Regulation in Human Liver Cells by High-throughput Sequencing
- Transcriptional and Epigenetic Regulation of Human CD4+ T Helper Lineage Specification
- Methylated DNA Immunoprecipitation and High-Throughput Sequencing (MeDIP-seq) Using Low Amounts of Genomic DNA
- Normal Physiology of ACTH and GH Release in the Hypothalamus and Anterior Pituitary in Man
- Influence of CpG islands on chromatin structure
- Epigenetics and targeting mechanisms in Drosophila melanogaster
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