Global DNA Demethylation During Erythropoiesis in vivo
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Summary
DNA demethylation can occur globally during somatic cell differentiation, providing an experimental model for its study in development and disease.
- Type
- article
- Published
- 2011-11-11
- Cited by
- 166
- References
- 39
- OpenAlex
- https://openalex.org/W1964941502
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:206534714
Keywords
DNA demethylation, DNA methylation, Biology, CpG site, Demethylation
References
- LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation.
- Intracellular hemoglobin-a specific marker for erythroid cells in paraffin sections. An immunoperoxidase study of normal, megaloblastic, and dysplastic erythropoiesis, including erythroleukemia and other myeloproliferative disorders.
- Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
- Gene structure and transcription in mouse cells with extensively demethylated DNA
- Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by Aid deficiency
- Rethinking how DNA Methylation Patterns are Maintained
- Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-α
- Diagnosis and characterization of acute erythroleukemia subsets by determining the percentages of myeloblasts and proerythroblasts in 69 cases
- Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus.
- Reprogramming towards pluripotency requires AID-dependent DNA demethylation
- Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction.
- Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication.
- Direct detection of methylated cytosine in DNA by use of the restriction enzyme MspI.
- BISMA - Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences
- The gamma-globin gene promoter progressively demethylates as the hematopoietic stem progenitor cells differentiate along the erythroid lineage in baboon fetal liver and adult bone marrow.
- A reversible arrest point in the late G1 phase of the mammalian cell cycle.
- 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy
- Negative Autoregulation by FAS Mediates Robust Fetal Erythropoiesis
- Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
- The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses
Cited by
- Functions of DNA methylation and hydroxymethylation in mammalian development.
- Primordial Germ Cell Differentiation in Vitro: A Model for Understanding Epigenetic Reprogramming and Genome-Wide DNA Demethylation in Mouse Primordial Germ Cells
- Understanding Ten-Eleven Translocation-2 in Hematological and Nervous Systems
- Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status.
- Interferon-γ mediates anemia but is dispensable for Fulminant Toll-Like Receptor 9-induced Macrophage Activation Syndrome and Hemophagocytosis
- Different Roles for Tet1 and Tet2 Proteins in Reprogramming-Mediated Erasure of Imprints Induced by EGC Fusion
- Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation
- Dissecting the epigenetic landscapes of hematopoiesis and fission yeast.
- The TET2 interactors and their links to hematological malignancies
- Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model
- A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors
- CD41 Marks the Initial Myelo‐Erythroid Lineage Specification in Adult Mouse Hematopoiesis: Redefinition of Murine Common Myeloid Progenitor
- Analysing and interpreting DNA methylation data
- DNA methylation: a promising landscape for immune system-related diseases.
- Hydroxymethylation at Gene Regulatory Regions Directs Stem/Early Progenitor Cell Commitment during Erythropoiesis
- Recent Synchronous Radiation of a Living Fossil
- Function of oncogenes in cancer development: a changing paradigm
- DNA methylation: roles in mammalian development
- High Resolution Methylome Analysis Reveals Widespread Functional Hypomethylation during Adult Human Erythropoiesis*
- DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy
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