The role of protein quality control in mitochondrial protein homeostasis under oxidative stress
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Summary
The ATP‐dependent protease Pim1/LON is identified as a major factor in the degradation of ROS‐modified soluble polypeptides localized in the matrix compartment, and it is proposed that this protease system performs a crucial protective function under oxidative stress conditions.
- Type
- article
- Published
- 2010-04-01
- Cited by
- 93
- References
- 64
- OpenAlex
- https://openalex.org/W1985760284
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8197100
Keywords
Mitochondrion, Oxidative stress, Proteases, Proteolysis, Biochemistry
References
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Cited by
- The role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis and activity control.
- Impaired protein quality control system underlies mitochondrial dysfunction in skeletal muscle of streptozotocin-induced diabetic rats.
- Stress-triggered Activation of the Metalloprotease Oma1 Involves Its C-terminal Region and Is Important for Mitochondrial Stress Protection in Yeast*
- The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways
- Interplay between Oxidative Stress, Inflammation, and Amyloidosis in the Anterior Segment of the Eye; Its Pathological Implications
- Links between Aging and Proteostasis Decline in Saccharomyces cerevisiae
- Protein profile and reactive oxygen species production in mitochondria from pigs divergently selected for residual feed intake
- Mitochondrial Protein Dynamics in Cardiac Remodeling
- Toxicogenomics : a transcriptomics approach to assess the toxicity of 4-nitrophenol to Sachharomyces cerevisiae
- Knowledge derivation and data mining strategies for probabilistic functional integrated networks
- Chaperone-protease networks in mitochondrial protein homeostasis.
- Multitasking in the mitochondrion by the ATP-dependent Lon protease
- An ATP-dependent protease homolog ensures basic standards of survival and pathogenicity for Magnaporthe oryzae
- Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system.
- Quantitative Proteomic Approaches and Their Application in the Study of Yeast Stress Responses
- Mitochondrial ATP-dependent proteases in protection against accumulation of carbonylated proteins.
- Attenuation of Mitochondrial Unfolded Protein Response is Associated With Hepatic Dysfunction in Septic Rats
- A Vanillin Derivative Causes Mitochondrial Dysfunction and Triggers Oxidative Stress in Cryptococcus neoformans
- Mitochondrial proteases and protein quality control in ageing and longevity.
- Stress-responsive regulation of mitochondria through the ER unfolded protein response.
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