Nuclear Maspin expression is associated with response to adjuvant 5‐fluorouracil based chemotherapy in patients with stage III colon cancer

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Summary

Patients with negative immunhistochemical Maspin expression do not benefit from 5‐FU treatment and may be candidates for an alternative (non‐5‐FU based) adjuvant therapy regime, which is highly predictive of 5-FU chemotherapy response in patients with advanced stage colon cancer.

Type
article
Published
2006-05-01
Cited by
56
References
50
Access
Open access

Keywords

Maspin, Medicine, Chemotherapy, Oncology, Colorectal cancer

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