A role of novel serpin maspin in tumor progression: The divergence revealed through efforts to converge
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Summary
Recent advances in the identification of maspin‐binding proteins and the potential underlying molecular mechanisms of masminogen activator and intracellular histone deacetylase 1 (HDAC1) are summarized.
- Type
- review
- Published
- 2006-12-01
- Cited by
- 37
- References
- 73
- OpenAlex
- https://openalex.org/W2036984883
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23177318
Keywords
Serpin, Maspin, Biology, Serine protease, Cancer research
References
- Histone deacetylase 1 (HDAC‐1) required for the normal formation of craniofacial cartilage and pectoral fins of the zebrafish
- Osteoblastic metastasis in advanced prostate cancer.
- The role of the plasminogen activation system in angiogenesis and metastasis.
- The Urokinase-type Plasminogen Activator System in Prostate Cancer Metastasis
- Maspin is an angiogenesis inhibitor
- Urokinase overproduction results in increased skeletal metastasis by prostate cancer cells in vivo.
- Production, purification, and characterization of recombinant maspin proteins.
- Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure
- The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin.
- Binding of single-chain prourokinase to the urokinase receptor of human U937 cells.
- Structure of the histone deacetylase SIRT2
- Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins.
- A 55,000-60,000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification.
- ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK).
- Macrophage and foam cell release of matrix-bound growth factors. Role of plasminogen activation.
- Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.
- Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
- The promise and challenge toward the clinical application of maspin in cancer.
- Gene Structure, Chromosomal Localization, and Expression of the Murine Homologue of Human Proteinase Inhibitor 6 (PI-6) Suggests Divergence of PI-6 from the Ovalbumin Serpins (*)
- Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3.
Cited by
- Characterisation of the cellular roles of the non-inhibitory serpin, maspin
- Serpin B5 is a CEA‐interacting biomarker for colorectal cancer
- The myoepithelial cell: its role in normal mammary glands and breast cancer.
- Evidence of post-translational modification of the tumor suppressor maspin under oxidative stress.
- Clinicopathological correlates and prognostic significance of maspin expression in 450 patients after potentially curative resection of node‐positive colonic cancer
- Clinical significance of Maspin promoter methylation and loss of its protein expression in invasive ductal breast carcinoma: correlation with VEGF-A and MTA1 expression
- The molecular phylogeny of uterine serpins and its relationship to evolution of placentation
- Loss of Maspin expression is a negative prognostic factor in common salivary gland tumors.
- Effects of 5-Aza-CdR on cell proliferation of breast cancer cell line MDA-MB-435S and expression of maspin gene
- Recent progress in understanding the diversity of the human ov-serpin/clade B serpin family
- Regulation of DNA synthesis and the cell cycle in human prostate cancer cells and lymphocytes by ovine uterine serpin
- Imatinib Mesylate Alters the Expression of Genes Related to Disease Progression in an Animal Model of Uveal Melanoma
- Candidate therapeutic agents for hepatocellular cancer can be identified from phenotype‐associated gene expression signatures
- Shift from cytoplasmic to nuclear maspin expression correlates with shorter overall survival in node-negative colorectal cancer.
- High expression of maspin is associated with early tumor relapse in breast cancer.
- Maspin and MCM2 immunoprofiling in salivary gland carcinomas
- uPAR mediates anticancer activity of PEDF
- Tumor progression and metastasis from genetic to microenvironmental determinants
- Nuclear, compared with combined nuclear and cytoplasmic expression of maspin, is linked in lung adenocarcinoma to reduced VEGF-A levels and in Stage I, improved survival
- Immunhistochemie als Prognoseindikator bei Speicheldrüsenkarzinomen
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