Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Keywords

Cell biology, Mitochondrion, Cytochrome c, Staurosporine, Apoptosis

References

• Bcl‐2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types.W. Zhu, Alison Cowie, Gihane W Wasfy — 1996
• Apoptotic pathways: paper wraps stone blunts scissors.Douglas R. Green — 2000
• Mitochondrial control of cell deathGuido Kroemer, John C. Reed — 2000
• BAX-dependent transport of cytochrome c reconstituted in pure liposomesMitsuyoshi Saito, Stanley J. Korsmeyer, Paul H. Schlesinger — 2000
• Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosisXiao‐Ming Yin, Kun Wang, Atan Gross — 1999
• Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDACShigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto — 1999
• tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c.Michael C. Wei, Tullia Lindsten, Vamsi K. Mootha — 2000
• The Bcl-2 protein family: arbiters of cell survival.Jerry M. Adams, Suzanne Cory — 1998
• Two CD95 (APO‐1/Fas) signaling pathwaysCarsten Scaffidi, Simone Fulda, Anu Srinivasan — 1998
• Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9.Keisuke Kuida, Tarik F. Haydar, Chia‐Yi Kuan — 1998
• A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes.Daniel Ory, Beverly I. Neugeboren, Richard C. Mulligan — 1996
• Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors.Xu Luo, I. Imawati Budihardjo, Hua Zou — 1998
• Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2Jürg Häcki, Lotti Egger, Laurent Monney — 2000
• Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.Kang Li, Yucheng Li, John M. Shelton — 2000
• The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.Tullia Lindsten, Andrea J. Ross, Ayala King — 2000
• Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members.Sheau Yu Hsu, Antti Kaipia, E. McGee — 1997
• Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-βToshiyuki Nakagawa, Hong Zhu, Nobuhiro Morishima — 2000
• p28 Bap31, a Bcl-2/Bcl-XL- and Procaspase-8–associated Protein in the Endoplasmic ReticulumFlorence W.H. Ng, Mai Nguyen, Tony Kwan — 1997
• Maintenance of Calcium Homeostasis in the Endoplasmic Reticulum by Bcl-2Huiling He, Minh Lam, Thomas S. McCormick — 1997
• Apaf1 is required for mitochondrial pathways of apoptosis and brain development.Hiroki Yoshida, Young‐Yun Kong, Ritsuko Yoshida — 1998

Cited by

• Investigation of the ubiquitin-specific protease UBP41 and of the lysosomal cysteine proteases cathepsin-L and cathepsin-B as potential mediators of proapoptotic signallingAndreas Gewies — 2004
• Apoptosis—New Opportunities for Novel Therapeutics for Heart DiseasesGiora Feuerstein — 2001
• Molecular Mechanisms of Programmed Necrotic Death Initiated by Intrinsic Death SignalsGary Xiaoshi Wang — 2014
• Biophysical Insights into the Oligomerization of Bclxl Apoptotic RepressorV. Bhat — 2013
• Hsp70: anti-apoptotic and tumorigenic protein.Anne-Laure Rérole, Gaëtan Jégo, Carmen Garrido — 2011
• The urokinase-system--role of cell proliferation and apoptosis.Ralf Hildenbrand, Mukesh Gandhari, Philipp Stroebel — 2008
• Insights into cancer therapeutic design based on p53 and TRAIL receptor signalingLuis García de Oteyza — 2001
• PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway眞理 青木, 美根子 猪俣, 道子 葉山 — 2002
• Mitochondria-Dependent Caspase-9 Activation Is Necessary for Antigen Receptor-Mediated Effector Caspase Activation and Apoptosis in WEHI 231 Lymphoma Cells1Jean Pierre Cavaillé — 2002
• Delayed Sclerosis, Neuroprotection, and Limbic Epileptogenesis After Status Epilepticus in the RatBret R. Fund, Maw‐Der Foo — 2002
• Early events of target deprivation/axotomy‐induced neuronal apoptosis in vivo: oxidative stress, DNA damage, p53 phosphorylation and subcellular redistribution of death proteinsRamon Vilaró — 2003
• Mitochondrion-targeted apoptosis regulators of viral origin.В. Г. Степанов, Е. Г. Панина, Т. Б. Морозов — 2003
• Alterations in the apoptotic machinery and their potential role in anticancer drug resistanceGabriel Anaya Duarte — 2003
• c-Myc Sensitization to Oxygen Deprivation-induced Cell Death Is Dependent on Bax/Bak, but Is Independent of p53 and Hypoxia-inducible Factor-1*Жанна Валерьяновна Петрунина, Александр Альфредович Шунейко — 2004
• The Bcl-2 family: roles in cell survival and oncogenesisEnric Marco Granell — 2003
• Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1Susumu Kurinobu — 2003
• Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosisA.D.M. Rayner — 2004
• Genetic approaches to analyzing mitochondrial outer membrane permeability.Вершинина Анна Павловна — 2004
• Control of mitochondrial permeability by Bcl-2 family members.Манаков Андрей Геннадьевич, Кривуля Ирина Владимировна — 2004
• Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.William Shakespeare — 2004

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