Apaf1 is required for mitochondrial pathways of apoptosis and brain development.

Keywords

Biology, Apoptosis, Programmed cell death, Caspase, Cell biology

References

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Cited by

• A concomitant ATP-depleting strategy markedly enhances anticancer agent activityDaniel Martín, David R. Spriggs, Jason A. Koutcher — 2001
• The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.Val Greenfield — 1999
• Regulation of the Fas Death Pathway by FLICE-Inhibitory Protein in Primary Human B Cells1Noelia Torralba Venegas — 2000
• Reduction of endogenous transforming growth factors β prevents ontogenetic neuron deathR. Payne, D.A. Toy — 2000
• 3-m-bromoacetylamino benzoic acid ethyl ester: a new cancericidal agent that activates the apoptotic pathway through caspase-9.Pau Viciano Navarro — 2000
• The ‘harmless’ release of cytochrome cWei Zhou — 2000
• Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia?Hansruedi Loetscher, Olivier Niederhauser, John A. Kemp — 2001
• The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr.Vincent‐Wayne Mitchell, M K Hogg — 2003
• ANTICANCER ACTIVITY OF NATURAL HEALTH PRODUCTS (DANDELION ROOT & LONG PEPPER EXTRACTS); EXTENSIVE STUDY OF EFFICACY AND MECHANISM OF ACTIONPamela Ovadje — 2014
• Alterations in the apoptotic machinery and their potential role in anticancer drug resistanceGabriel Anaya Duarte — 2003
• c-Myc Sensitization to Oxygen Deprivation-induced Cell Death Is Dependent on Bax/Bak, but Is Independent of p53 and Hypoxia-inducible Factor-1*Жанна Валерьяновна Петрунина, Александр Альфредович Шунейко — 2004
• The Bcl-2 family: roles in cell survival and oncogenesisEnric Marco Granell — 2003
• Coupling of caspase‐9 to Apaf1 in response to loss of pRb or cytotoxic drugs is cell‐type‐specificJean Delumeau — 2004
• Tumor Necrosis Factor Death Receptor Signaling Cascade Is Required for Amyloid-β Protein-Induced Neuron Death達也 馬渡, 玲子 芳川, Kristina Lindholm — 2004
• Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevanceJordi Valls Clua — 2004
• Caspase-7 Expanded Function and Intrinsic Expression Level Underlies Strain-Specific Brain Phenotype of Caspase-3-Null MiceCaroline Houde, Kathleen G. Banks, Nathalie Coulombe — 2004
• Deregulated expression of ΔNp73α causes early embryonic lethalityCharles Grimsdale — 2006
• Loss of Gli3 enhances the viability of embryonic telencephalic cells in vitroSupini Damun — 2005
• Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice overexpressing Hsp70.裕 金築, 洋 平井, 陸郎 小川 — 2006
• Big wheel keeps on turning: apoptosome regulation and its role in chemoresistanceKok Ming Ng — 2008

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