The landscape of cancer genes and mutational processes in breast cancer

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Summary

Strong correlations between mutation number, age at which cancer was diagnosed and cancer histological grade are found, and multiple mutational signatures are observed, including one present in about ten per cent of tumours characterized by numerous mutations of cytosine at TpC dinucleotides.

Type
article
Published
2012-05-16
Cited by
1,742
References
39
Access
Open access

Keywords

Biology, Breast cancer, Genetics, Gene, Cancer

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