Long noncoding RNAs: functional surprises from the RNA world.
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Summary
Most of the eukaryotic genome is transcribed, yielding a complex network of transcripts that includes tens of thousands of long noncoding RNAs with little or no protein-coding capacity.
- Type
- review
- Published
- 2009-07-01
- Cited by
- 2,285
- References
- 135
- Access
- Open access
- OpenAlex
- https://openalex.org/W1978967539
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:41723599
Keywords
Biology, Long non-coding RNA, Non-coding RNA, Small nucleolar RNA, RNA
References
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- DD3(PCA3), a very sensitive and specific marker to detect prostate tumors.
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- N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts
- A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains
- Role of Dicer in posttranscriptional RNA silencing.
- Bidirectional promoters generate pervasive transcription in yeast
- Vegetal localization of maternal mRNAs is disrupted by VegT depletion.
- A Rae1-containing ribonucleoprotein complex is required for mitotic spindle assembly.
- Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene
- Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
- Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to breast cancer
- MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
- Polycomb proteins targeted by a short repeat RNA to the mouse X-chromosome
- A role for noncoding transcription in activation of the yeast PHO5 gene
- A new frontier for molecular medicine: noncoding RNAs.
- A Chromosomal Memory Triggered by Xist Regulates Histone Methylation in X Inactivation
Cited by
- Ancient roles of non-coding RNAs in eukaryotic evolution
- Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse
- [Technological advances in single-cell genomic analyses].
- Human long non‐coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors
- Regulation of an antisense RNA with the transition of neonatal to IIb myosin heavy chain during postnatal development and hypothyroidism in rat skeletal muscle.
- Hepatitis B virus X protein (HBx)‐related long noncoding RNA (lncRNA) down‐regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin
- Epigenetics in Sports
- WITHDRAWN: Down-regulation of long non-coding RNA TUG1 suppresses melanoma cell proliferation and induces apoptosis via up-regulating microRNA-9.
- MALAT1 promotes the proliferation and metastasis of gallbladder cancer cells by activating the ERK/MAPK pathway
- Long Noncoding RNAs and Hepatocellular Carcinoma
- lincRNA HOTAIR as a novel promoter of cancer progression
- Low expression of long noncoding RNA PANDAR predicts a poor prognosis of non-small cell lung cancer and affects cell apoptosis by regulating Bcl-2
- Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression
- Downregulation of the long noncoding RNA EGOT correlates with malignant status and poor prognosis in breast cancer
- Linc-ROR induces epithelial-mesenchymal transition and contributes to drug resistance and invasion of breast cancer cells
- Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia
- Ovarian transcriptomic study reveals the differential regulation of miRNAs and lncRNAs related to fecundity in different sheep
- Alternative splicing of the OCC-1 gene generates three splice variants and a novel exonic microRNA, which regulate the Wnt signaling pathway
- Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis
- Serum Exosomal Long Noncoding RNAs ENSG00000258332.1 and LINC00635 for the Diagnosis and Prognosis of Hepatocellular Carcinoma
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