Electrophoretically silent hemoglobin mutants as revealed by isoelectric focusing in immobilized pH gradients
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Summary
Immobilized pH gradients appear to be an excellent tool for screening of genetic polymorphism and for detecting “silent mutants”, i.
- Type
- article
- Published
- 1989-01-01
- Cited by
- 6
- References
- 20
- OpenAlex
- https://openalex.org/W1975607842
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10231259
Keywords
Isoelectric focusing, Immobilized pH gradient, Hemoglobin, Mutant, Chromatography
References
- New directions in electrophoretic methods
- Immobilized pH gradients and reversed-phase high-performance liquid chromatography: a strategy for characterization of haemoglobin variants with electrophoretic mobility identical to that of Hb A. The case of Hb San Diego.
- Isoelectric focusing in immobilized pH gradients: theory and newer methodology.
- Isoelectric Focusing: Theory, Methodology, and Applications
- Hemoglobin polymorphism in the domestic dog.
- Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G‐250 and R‐250
- Isoelectric focusing in gels.
- Isoelectric focusing in immobilized pH gradients: principle, methodology and some applications.
- Extended application of RP-HPLC for characterization of human hemoglobin variants.
- Detection of electrophoretically silent mutations by immobilized pH gradients.
- Isoelectric focusing of tryptic peptides from hemoglobin subunits by immobilized pH gradients.
- Electrophoretic and chromatographic techniques for the differential diagnosis of a haemoglobin abnormality: Hb E heterozygosity.
- Detection of neutral amino acid mutations by immobilized pH gradients: The case of the Tγ variant in fetal hemoglobin Sardinia
- Detection of neutral amino acid substitutions in proteins.
Cited by
- Disorders of the synthesis of human fetal hemoglobin
- Immobilized pH gradients
- Analysis of Haemoglobin Variants Using Immobilized pH Gradients
- Solute Focusing Techniques for Bioseparations
- Electrophoretic methods for study of hemoglobins.
- The evolutionary history of the European rabbit ( Oryctolagus cuniculus ): major patterns of population differentiation and geographic expansion inferred from protein polymorphism
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- Chromatofocusing and isoelectric focusing in immobilized pH gradients compared for characterization of human hemoglobin variants.
- [Isoelectric heterogeneity of hemoglobin of domestic ducks].