Obesity and genetics regulate microRNAs in islets, liver and adipose of diabetic mice
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Summary
To understand the relationship between miRNA regulation and obesity-induced diabetes, quantitatively profiled approximately 220 miRNAs in pancreatic islets, adipose tissue, and liver from diabetes-resistant and diabetes-susceptible mice to elucidate the genetic architecture of hepatic miRNA expression.
- Type
- article
- Published
- 2009-08-01
- Cited by
- 150
- References
- 52
- Access
- Open access
- OpenAlex
- https://openalex.org/W1972907318
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7906864
Keywords
Biology, microRNA, Adipose tissue, Obesity, Endocrinology
References
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- Genetic and genomic studies of the BTBR ob/ob mouse model of type 2 diabetes.
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Cited by
- Genetic and epigenetic determinants of inter-individual variability in responses to toxicants
- Dysregulated miR-103 and miR-143 expression in peripheral blood mononuclear cells from induced prediabetes and type 2 diabetes rats.
- MicroRNAs in adipogenesis and as therapeutic targets for obesity
- The Genotype-Tissue Expression (GTEx) project
- Identification of microRNA-132/212 function in vivo
- Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells.
- Re‐dicing the pancreatic β‐cell: do microRNAs define cellular identity?
- Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population
- Dissecting the microRNA pathway in the pancreatic β-cell during insulin resistance
- The physiological and pathophysiological roles of adipocyte miRNAs.
- Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets
- Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell
- MicroRNAs with Specific Roles in Diabetes and Psychiatric Diseases
- MicroRNA-dependent cross-talk between VEGF and HIF1α in the diabetic retina.
- High-Throughput Sequencing of microRNAs in Peripheral Blood Mononuclear Cells: Identification of Potential Weight Loss Biomarkers
- miRNAs and diabetes mellitus
- Low Stress Reactivity and Neuroendocrine Factors in the BTBR T+tf/J Mouse Model of Autism
- Postprandial Regulation of Hepatic MicroRNAs Predicted to Target the Insulin Pathway in Rainbow Trout
- Comparative MicroRNA Expression Profiles of Cynomolgus Monkeys, Rat, and Human Reveal that miR-182 Is Involved in T2D Pathogenic Processes
- Metabolic syndrome components in murine models
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