Genetic and epigenetic determinants of inter-individual variability in responses to toxicants
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Summary
Among the many possible epigenetic experimental methodologies, assessment of chromatin accessibility coupled with total RNA levels provides a cost-effective and comprehensive option to sufficiently characterize the complexity of epigenetic and regulatory activity in the context of understanding the inter-individual variability in responses to toxicants.
- Type
- article
- Published
- 2017-09-12
- Cited by
- 10
- References
- 103
- Access
- Open access
- OpenAlex
- https://openalex.org/W29276797
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43538254
Keywords
Psychology
References
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- Obesity and genetics regulate microRNAs in islets, liver and adipose of diabetic mice
- Epigenetic Alterations in Liver of C57BL/6J Mice after Short-Term Inhalational Exposure to 1,3-Butadiene
- Replication and Narrowing of Gene Expression Quantitative Trait Loci using Inbred Mice
Cited by
- Tissue- and strain-specific effects of a genotoxic carcinogen1,3-butadiene on chromatin and transcription
- Challenges in designing and executing clinical trials in a dish studies.
- Dotting the eyes: mouse strain dependency of the lens epithelium to low dose radiation-induced DNA damage
- Population-based analysis of DNA damage and epigenetic effects of 1,3-butadiene in the mouse
- How do cancer-sniffing dogs sort biological samples? Exploring case-control samples with non-targeted LC-Orbitrap, GC-MS, and immunochemistry methods
- Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion
- Intra- and inter-species variability in urinary N7-(1-hydroxy-3-buten-2-yl) guanine (EB-GII) adducts following inhalation exposure to 1,3-butadiene
- Genome-wide cancer-specific chromatin accessibility patterns derived from archival processed xenograft tumors
- Using liver models generated from human-induced pluripotent stem cells (iPSCs) for evaluating chemical-induced modifications and disease across liver developmental stages
- Welchen Einfluss hat die Wohnumgebung auf die Grundschulwahl der Eltern? Analysen zur Bedeutung von kontextuellen und familiären Merkmalen auf das Wahlverhalten
- Chromatin Accessibility as a Strategy to Detect Changes Associated With Development, Disease, and Exposure and Susceptibility to Chemical Toxins
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