Mechanisms Underlying Inflammation in Neurodegeneration
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Summary
There is evidence for a remarkable convergence in the mechanisms responsible for the sensing, transduction, and amplification of inflammatory processes that result in the production of neurotoxic mediators in neurodegenerative diseases.
- Type
- review
- Published
- 2010-03-19
- Cited by
- 3,395
- References
- 153
- Access
- Open access
- OpenAlex
- https://openalex.org/W1965942744
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4930569
Keywords
Biology, Neurodegeneration, Inflammation, Neuroscience, Disease
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- Converging actions of alcohol on liver and brain immune signaling.
- Autophagy Shapes Inflammation
- STAT3 inhibitors attenuate interferon-γ-induced neurotoxicity and inflammatory molecule production by human astrocytes.
- Paeonol attenuates H₂O₂-induced NF-κB-associated amyloid precursor protein expression.
- Design and in vitro characterization of PAC1/VPAC1-selective agonists with potent neuroprotective effects.
- Targeting reactive astrogliosis by novel biotechnological strategies.
- NeurimmiRs: microRNAs in the neuroimmune interface.
- Genetic Ablation of PLA2G6 in Mice Leads to Cerebellar Atrophy Characterized by Purkinje Cell Loss and Glial Cell Activation
- A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer's Disease
- Is the CCR5 Δ 32 Mutation Associated with Immune System-Related Diseases?
- Optineurin and amyotrophic lateral sclerosis
- Target- and Mechanism-Based Therapeutics for Neurodegenerative Diseases: Strength in Numbers
- Copper-β-amyloid peptides exhibit neither monooxygenase nor superoxide dismutase activities.
- Effects of Panax ginseng in Neurodegenerative Diseases
- Microglia in juvenile neuronal ceroid lipofuscinosis are primed toward a pro‐inflammatory phenotype
- The Neuroprotective Effect of Fisetin in the MPTP Model of Parkinson's Disease
- Tangeretin exerts anti-neuroinflammatory effects via NF-κB modulation in lipopolysaccharide-stimulated microglial cells.
- Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling
- Exploring Alzheimer Molecular Pathology in Down's Syndrome Cerebrospinal Fluid
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