Endogenous human microRNAs that suppress breast cancer metastasis
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Summary
It is shown that restoring the expression of these microRNAs in malignant cells suppresses lung and bone metastasis by human cancer cells in vivo, and miR-126 restoration reduces overall tumour growth and proliferation, whereasmiR-335 inhibits metastatic cell invasion.
- Type
- article
- Published
- 2008-01-10
- Cited by
- 1,911
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W1965371218
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2527843
Keywords
Metastasis, microRNA, Cancer research, Breast cancer, Biology
References
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- Metastasis suppressors alter the signal transduction of cancer cells
- Sox‐4 facilitates thymocyte differentiation
Cited by
- Bases moleculares de los nuevos tratamientos del carcinoma hepatocelular
- RARs and microRNAs.
- microRNAs in Cancer: biological effects of microRNAs in colorectal cancer
- Research on aromatase gene (CYP19A1) polymorphisms as a predictor of endocrine therapy effectiveness in breast cancer.
- Molecular treatment strategies and surgical reconstruction for metastatic bone diseases.
- A microRNA DNA methylation signature for human cancer metastasis
- Metastasis: from dissemination to organ-specific colonization
- MicroRNAs in breast cancer
- Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro.
- Overexpressed miR-494 down-regulates PTEN gene expression in cells transformed by anti-benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxide.
- Expression of tenascin-C and its isoforms in the breast
- Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease
- Highly sensitive detection of microRNA by chemiluminescence based on enzymatic polymerization
- MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer
- Interplay between β1-Integrin and Rho Signaling Regulates Differential Scattering and Motility of Pancreatic Cancer Cells by Snail and Slug Proteins*
- MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma.
- The involvement of microRNAs in malignant transformation.
- The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic sites
- Dissecting the telomere-independent pathways underlying human cellular senescence
- MicroRNAs associated with tumour migration, invasion and angiogenic properties in A549 and SK-Lu1 human lung adenocarcinoma cells.
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