Precise localization of m6A in Rous sarcoma virus RNA reveals clustering of methylation sites: implications for RNA processing
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Summary
A method for localizing and quantitating m6A within a large RNA molecule, the genomic RNA of Rous sarcoma virus, and observing a high frequency of methylation at PuGm6ACU sequences is described.
- Type
- article
- Published
- 1985-09-01
- Cited by
- 208
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W1909623163
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38521818
Keywords
Biology, RNA, Rous sarcoma virus, Molecular biology, RNase P
References
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- Methylation of nuclear simian virus 40 RNAs
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- Filamentous coliphage M13 as a cloning vehicle: insertion of a HindII fragment of the lac regulatory region in M13 replicative form in vitro.
- Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro.
Cited by
- Arabidopsis m6A demethylase activity modulates viral infection of a plant virus and the m6A abundance in its genomic RNAs
- N6-methyladenosine (m6A): Revisiting the Old with Focus on New, an Arabidopsis thaliana Centered Review
- Einfluss von Adenosin-2'-3'-Dialdehyd auf das Methylierungspotential und die Genexpression in HepG2-Zellen unter normoxischen Bedingungen
- Nucleoside Modifications Suppress RNA Activation of Cytoplasmic RNA Sensors
- Human herpesvirus 6: the virus and the search for its role as a human pathogen.
- In vitro synthesis of infectious retroviral RNA
- Methylation of mRNA.
- Mapping and significance of the mRNA methylome
- Characterization and partial purification of mRNA N6-adenosine methyltransferase from HeLa cell nuclei. Internal mRNA methylation requires a multisubunit complex.
- Yeast m6A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment
- N6-methyladenosine residues in an intron-specific region of prolactin pre-mRNA
- HNRNPA2B1 is a mediator of m6A-dependent nuclear RNA processing events
- Investigating the enzymology and molecular function of 5-methylctosine in RNA
- Unequal distribution of N6-methyladenosine in influenza virus mRNAs
- Posttranscriptional regulation of retroviral gene expression: primary RNA transcripts play three roles as pre-mRNA, mRNA, and genomic RNA
- Noncoding region between the env and src genes of Rous sarcoma virus influences splicing efficiency at the src gene 3' splice site
- Sprouts of RNA epigenetics
- A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA
- The formation of internal 6-methyladenine residues in eucaryotic messenger RNA.
- Effects of the S-adenosylhomocysteine hydrolase inhibitors 3-deazaadenosine and 3-deazaaristeromycin on RNA methylation and synthesis.
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