A novel U1/U5 interaction indicates proximity between U1 and U5 snRNAs during an early step of mRNA splicing.
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Summary
The authors' data indicate proximity between U1 and U5 snRNPs before the first catalytic step of splicing, and may suggest that U1 helps to direct U5 to the 5' splice site.
- Type
- article
- Published
- 1997-04-01
- Cited by
- 30
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W2284602184
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43168131
Keywords
snRNP, RNA splicing, Small nuclear RNA, Biology, Oligonucleotide
References
No references recorded for this paper.
Cited by
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- Functional recognition of 5' splice site by U4/U6.U5 tri-snRNP defines a novel ATP-dependent step in early spliceosome assembly.
- A Single Catalytically Active Subunit in the Multimeric Sulfolobus shibatae CCA-adding Enzyme Can Carry Out All Three Steps of CCA Addition*
- Dynamics of the U1 Small Nuclear Ribonucleoprotein during Yeast Spliceosome Assembly*
- Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome.
- Retroviral Splicing Suppressor Sequesters a 3′ Splice Site in a 50S Aberrant Splicing Complex
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- A statistical approach for 5′ splice site prediction using short sequence motifs and without encoding sequence data
- Functional analysis of the U5 snRNA loop 1 in the second catalytic step of yeast pre‐mRNA splicing
- Probing Interactions between the U2 Small Nuclear Ribonucleoprotein and the DEAD-box Protein, Prp5*
- The role of U5 snRNP in pre‐mRNA splicing
- ATP-dependent interaction of yeast U5 snRNA loop 1 with the 5' splice site.
- Reversible inhibition of the second step of splicing suggests a possible role of zinc in the second step of splicing.
- Mutations in U5 snRNA loop 1 influence the splicing of different genes in vivo.
- The conserved 3' end domain of U6atac snRNA can direct U6 snRNA to the minor spliceosome.
- An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8
- The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p.
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