A brief histone in time: understanding the combinatorial functions of histone PTMs in the nucleosome context.
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Summary
Overall, research on histone modifications has yielded great mechanistic insights into the regulation of genomic functions, and extending these studies using nucleosomes will further elucidate the complexity of these pathways in a more physiologically relevant context.
- Type
- review
- Published
- 2016-02-01
- Cited by
- 23
- References
- 124
- OpenAlex
- https://openalex.org/W1908716879
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36661324
Keywords
Histone code, Histone, Histone methylation, Nucleosome, Computational biology
References
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- Regulation of transcription by a protein methyltransferase.
- Use of selectively trypsinized nucleosome core particles to analyze the role of the histone "tails" in the stabilization of the nucleosome.
Cited by
- Innate immune memory in plants.
- Epigenetic modulations in early endothelial cells and DNA hypermethylation in human skin after sulfur mustard exposure.
- Recognition of the nucleosome by chromatin factors and enzymes
- Exogenous nucleosome-binding molecules: a potential new class of therapeutic drugs.
- Regulation of Cellular Immune Responses in Sepsis by Histone Modifications.
- Phosphorylated Histone 3 at Serine 10 Identifies Activated Spinal Neurons and Contributes to the Development of Tissue Injury-Associated Pain
- Shaping the Cellular Landscape with Set2/SETD2 Methylation
- Cryo-electron microscopy of chromatin biology
- Reading chromatin signatures after DNA double-strand breaks
- Innate immune memory: An evolutionary perspective
- Methods for chemical mapping of O-GlcNAc in the Drosophila genome
- The big picture of chromatin biology by cryo-EM.
- Ubiquitylated H2A.Z is associated with diverse types of silenced chromatin including methylated CpG islands and homopurine/homopyrimidine sequences
- Characterization of Nucleosomes Containing Specific Forms of the Histone Variant H2A.Z
- The Use of Mononucleosome Immunoprecipitation for Analysis of Combinatorial Histone Post-translational Modifications and Purification of Nucleosome-Interacting Proteins
- The epigenetic–metabolic interplay in gliomagenesis
- Epigenetic mechanisms regulate sex-specific bias in disease manifestations
- Unnatural Amino Acid Crosslinking for Increased Spatiotemporal Resolution of Chromatin Dynamics
- The role of abnormal epigenetic regulation of small GTPases in glioma (Review)
- Cross-kingdom mechanisms of trained immunity in plant systemic acquired resistance
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