NO Says Yes to Mitochondria
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Summary
The gas nitric oxide activates a transcriptional coactivator that directs expression of genes, which induce mitochondrial biogenesis, which boosts the number of mitochondria in their cells when the authors need to generate more heat or to work their muscles harder.
- Type
- letter
- Published
- 2003-02-07
- Cited by
- 69
- References
- 10
- OpenAlex
- https://openalex.org/W1545371073
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28505538
Keywords
Mitochondrion, Philosophy, Biology, Cell biology
References
- Biochemistry of Mitochondrial Nitric-oxide Synthase*
- Reactions between nitric oxide and haemoglobin under physiological conditions
- L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.
- Nuclear activators and coactivators in mammalian mitochondrial biogenesis.
- Endothelial nitric oxide synthase (NOS) deficiency affects energy metabolism pattern in murine oxidative skeletal muscle.
- Does nitric oxide modulate mitochondrial energy generation and apoptosis?
- Effects of nitric oxide on proliferation and differentiation of rat brown adipocytes in primary cultures
- Mitochondrial Biogenesis in Mammals: The Role of Endogenous Nitric Oxide
- Nitric oxide inhibition of mitochondrial respiration and its role in cell death
- Serial Review: Nitric Oxide in Mitochondria Guest Editors: Christoph Richter and Matthias Schweizer NITRIC OXIDE INHIBITION OF MITOCHONDRIAL RESPIRATION AND ITS ROLE IN CELL DEATH
Cited by
- Contrasting potential of nitric oxide and peroxynitrite to mediate oligodendrocyte injury in multiple sclerosis
- Links between Aging and Proteostasis Decline in Saccharomyces cerevisiae
- Effects of core temperature on exercise-induced mitochondrial biogenesis: Potential role of PGC-1α, AMPK eNOS, SIRT1, and SIRT3
- Improved bioenergetic recovery during experimental ischemia and reperfusion by irradiation
- Identification of tyrosine‐nitrated proteins in HT22 hippocampal cells during glutamate‐induced oxidative stress
- In Vitro and in Vivo Therapeutics of β-Thujaplicin on Lps-Induced Inflammation in Macrophages and Septic Shock in Mice
- Biologia, patobiología, bioclínica y farmacoterapéutica de la di-metil-arginina asimétrica (ADMA) en la especie humana
- Electrochemical nitric oxide microsensors based on two-dimensional cross-linked polymeric LB films of oligo(dimethylsiloxane) copolymer
- Irradiation at 634 nm releases nitric oxide from human monocytes
- Mitochondrial free radical production and cell signaling.
- Brain mitochondrial nitric oxide synthase: in vitro and in vivo inhibition by chlorpromazine.
- Chrysanthemum zawadskii var. latilobum extract inhibits the production of nitric oxide and PGE2 through inducible nitric oxide synthase (iNOS) and cyclooxygenase-2(COX-2) in RAW 264. 7 cells
- Improvement of mouse brain mitochondrial function after deprenyl treatment.
- Immunostimulatory activities of β-d-glucan from Ganoderma Lucidum.
- Say NO to fibromyalgia and chronic fatigue syndrome: an alternative and complementary therapy to aerobic exercise.
- Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease.
- Rat brain and liver mitochondria develop oxidative stress and lose enzymatic activities on aging.
- Amperometric nitric oxide microsensor using two-dimensional cross-linked Langmuir-Blodgett films of polysiloxane copolymer
- Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by a novel compound, mercaptopyrazine, through suppression of nuclear factor-kappaB binding to DNA.
- The Function and Pathology of Brown Adipose Tissue in Animals and Humans
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