The Progression in the Mouse Skin Carcinogenesis Model Correlates With ERK1/2 Signaling
Explore this paper's citation graph
Summary
These data suggest, for the first time, that oncogenicity and the degree of progression in the mouse skin carcinogenesis model correlates with ERK1/2 signaling.
- Type
- article
- Published
- 2002-10-01
- Cited by
- 10
- References
- 73
- Access
- Open access
- OpenAlex
- https://openalex.org/W1484786684
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17711178
Keywords
Carcinogenesis, Molecular medicine, Signal transduction, Cancer research, Biology
References
- Kinetic and biochemical correlation between sustained p44ERK1 (44 kDa extracellular signal-regulated kinase 1) activation and lysophosphatidic acid-stimulated DNA synthesis in Rat-1 cells.
- Transcriptional regulation of cell invasion: AP-1 regulation of a multigenic invasion programme.
- Regulation of Fra-1 and Fra-2 phosphorylation differs during the cell cycle of fibroblasts and phosphorylation in vitro by MAP kinase affects DNA binding activity.
- Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
- Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation.
- Evidence for the in vitro and in vivo interaction of Ras with protein kinase C zeta.
- Oncogene activation in chemical carcinogenesis.
- Phosphatidylinositol-3-OH kinase direct target of Ras
- Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor.
- Epithelial Cell Plasticity in Development and Tumor Progression
- Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
- Activation of extracellular signal‐regulated kinase, ERK2, by p21ras oncoprotein.
- Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia
- Oncogenic Ras Downregulates Rac Activity, Which Leads to Increased Rho Activity and Epithelial–Mesenchymal Transition
- A synthetic inhibitor of the mitogen-activated protein kinase cascade.
- ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK.
- Proteins regulating Ras and its relatives
- Direct Interaction between Ras and the Kinase Domain of Mitogen-activated Protein Kinase Kinase Kinase (MEKK1) (*)
- Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
- Desensitization of Ras Activation by a Feedback Disassociation of the SOS-Grb2 Complex (*)
Cited by
- Expression profile and interactions of hnRNP A3 within hnRNP/mRNP complexes in mammals.
- Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
- Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation
- ERK2 dependent signaling contributes to wound healing after a partial-thickness burn.
- p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.
- The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development.
- Alterations in signal transduction pathways implicated in tumour progression during multistage mouse skin carcinogenesis.
- Die Rolle des Arylhydrokarbon-Rezeptors in der UVB-induzierten Signaltransduktion
- Essential Oil of Mentha aquatica var. Kenting Water Mint Suppresses Two-Stage Skin Carcinogenesis Accelerated by BRAF Inhibitor Vemurafenib
- Cross-talk of Aryl Hydrocarbon Receptor (AHR)- and Vitamin D Receptor (VDR)-signaling in Human Keratinocytes
Related papers
- Tumorigenesis and cell evolution.
- Progress of the relationship between aberrant p53 protein and tumorigenesis
- Metastasis suppressors Nm23H1 and Nm23H2 differentially regulate neoplastic transformation and tumorigenesis.
- Psychogenic carcinogenesis: carcinogenesis is without exogenic carcinogens.
- miR-21 regulates N-methyl-N-nitro-N'-nitrosoguanidine-induced gastric tumorigenesis by targeting FASLG and BTG2.
- Inflammation and Carcinogenesis
- Inhibition of both skin and lung tumorigenesis by Car‐R mouse‐derived cancer modifier loci
- Circular RNA circIL21R promotes cervical cancer cells proliferation and migration by sponging the miR-1205/PTBP1 axis.
- Molecular-genetic mechanisms underlying oral oncogenesis (review).