Modelling the endothelial cell response to fluid flow
Explore this paper's citation graph
Summary
This research shows that local signalling in endothelial cells could be initiated by the force normal to the surface of the cell and maintained by limited diffusion, indicating the EC signalling response to fluid flow may be attenuated by a change in morphology.
- Type
- dissertation
- Published
- 2009-05-01
- Cited by
- 1
- References
- 160
- OpenAlex
- https://openalex.org/W646503904
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:106478215
Keywords
Cell biology, GTPase, Focal adhesion, Signal transduction, Transduction (biophysics)
References
- Membrane association and targeting of prenylated Ras-like GTPases.
- A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
- Mathematical Model for Spatial Segregation of the Rho-Family GTPases Based on Inhibitory Crosstalk
- Vascular endothelium in atherosclerosis
- N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility
- The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments
- Shear flow over a protuberance on a plane wall
- Rho GTPases and cell migration.
- Flow-mediated endothelial mechanotransduction.
- Cell motility driven by actin polymerization.
- Crystal Structure of Arp2/3 Complex
- Eukaryotic Chemotaxis: Distinctions between Directional Sensing and Polarization*
- A Mass Conserved Reaction–Diffusion System Captures Properties of Cell Polarity
- Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism.
- Cell Spreading and Lamellipodial Extension Rate Is Regulated by Membrane Tension
- Evolution of the Rho family of ras-like GTPases in eukaryotes.
- Processive capping by formin suggests a force-driven mechanism of actin polymerization
- Modeling cell rheology with the Subcellular Element Model
- Analysis of actin filament network organization in lamellipodia by comparing experimental and simulated images
- Designing biosensors for Rho family proteins — deciphering the dynamics of Rho family GTPase activation in living cells
Cited by
Related papers
- How Cells Integrate Complex Stimuli: The Effect of Feedback from Phosphoinositides and Cell Shape on Cell Polarization and Motility
- Directional migration of the neural crest:an interplay between contact inhibition of locomotion andco-attraction
- Computational models on cell migration
- On the theory of cell migration: durotaxis and chemotaxis
- Engineering Tools for Studying Coordination Between Biochemical and Biomechanical Activities in Cell Migration