Genes of innate immunity and their significance in evolutionary ecology of free livings rodents
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Summary
The results suggest that purifying selection has been a dominant force in evolution of the Tlr4 and Tlr7 genes, but it is demonstrated that episodic diversification selection has shaped the present species-specific variation in rodent Tlrs.
- Type
- preprint
- Published
- 2013-12-19
- Cited by
- 1
- References
- 110
- Access
- Open access
- OpenAlex
- https://openalex.org/W355277407
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:83446203
Keywords
Biology, Innate immune system, Genetics, Gene, Acquired immune system
References
- Evolution of the TIR domain-containing adaptors in humans: swinging between constraint and adaptation.
- The acquired immune system: a vantage from beneath.
- Toll and Toll-Like Receptors:: An Immunologic Perspective
- A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
- Primer3 on the WWW for general users and for biologist programmers.
- Phylogenetic variation and polymorphism at the Toll-like receptor 4 locus (TLR4)
- Translational Mini‐Review Series on Toll‐like Receptors: Networks regulated by Toll‐like receptors mediate innate and adaptive immunity
- MHC studies in nonmodel vertebrates: what have we learned about natural selection in 15 years?
- Signatures of selection acting on the innate immunity gene Toll‐like receptor 2 (TLR2) during the evolutionary history of rodents
- Pathogen-mediated selection for MHC variability in wild zebrafish
- CONTRASTING PATTERNS OF DIVERSITY AND POPULATION DIFFERENTIATION AT THE INNATE IMMUNITY GENE TOLL‐LIKE RECEPTOR 2 (TLR2) IN TWO SYMPATRIC RODENT SPECIES
- Variation matters: TLR structure and species-specific pathogen recognition.
- Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
- Immune signaling by RIG-I-like receptors
- SMART, a simple modular architecture research tool: identification of signaling domains.
- Evolution of the chicken Toll-like receptor gene family: A story of gene gain and gene loss
- Characterization of bovine Toll-like receptor 8: ligand specificity, signaling essential sites and dimerization.
- Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
- Duplication, balancing selection and trans-species evolution explain the high levels of polymorphism of the DQA MHC class II gene in voles (Arvicolinae)
- Pathogen recognition and innate immunity.
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