Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.
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Summary
A direct involvement of TNF in the pathogenesis of arthritis is indicated and transgenic mice which predictably develop arthritis represent a novel genetic model by which the pathogenic and treatment of this disease in humans may be further investigated.
- Type
- article
- Published
- 1991-12-01
- Cited by
- 1,658
- References
- 2
- Access
- Open access
- OpenAlex
- https://openalex.org/W132781887
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24945794
Keywords
Molecular genetics, Biology, Library science, Genetics, Gene
References
No references recorded for this paper.
Cited by
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- Differentially regulated expression of growth differentiation factor 5 and bone morphogenetic protein 7 in articular cartilage and synovium in murine chronic arthritis: potential importance for cartilage breakdown and synovial hypertrophy.
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- Developments in the scientific understanding of rheumatoid arthritis
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- Macrophages in Synovial Inflammation
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- Review: Animal Models as a Tool to Dissect Pivotal Pathways Driving Spondyloarthritis
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