Transcriptional control of human p53-regulated genes
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Summary
The most comprehensive list so far of human p53-regulated genes and their experimentally validated, functional binding sites that confer p53 regulation is presented.
- Type
- article
- Published
- 2008-05-01
- Cited by
- 1,971
- References
- 200
- OpenAlex
- https://openalex.org/W18431400
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:933265
Keywords
Art, Humanities, Indie film, Visual arts
References
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- Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53
- Pidd, a new death-domain–containing protein, is induced by p53 and promotes apoptosis
- Surfing the p53 network
- A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
- Cloning of P2XM, a novel human P2X receptor gene regulated by p53.
- Identification of novel p53 target genes in ionizing radiation response.
- p53 stimulates transcription from the human transforming growth factor alpha promoter: a potential growth-stimulatory role for p53
- Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.
- A transcriptionally active DNA-binding site for human p53 protein complexes
- Transcriptional activation of the human epidermal growth factor receptor promoter by human p53
- Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53.
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- Redefining the p53 response element
- Chemosensitivity profiles identify polymorphisms in the p53 network genes 14-3-3tau and CD44 that affect sarcoma incidence and survival.
- Transcriptional regulation of cellular senescence
- Sensitive single-molecule protein quantification and protein complex detection in a microarray format
- p53 can repress transcription of cell cycle genes through a p21WAF1/CIP1-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements
- Another fork in the road—life or death decisions by the tumour suppressor p53
- Critical and Independent Roles of the P/CAF Acetyltransferase in ARF-p53 Signaling: A Dissertation
- Tumor suppressor p53 and its mutants in cancer metabolism
- Reactive Oxygen Species in Normal and Tumor Stem Cells
- RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38
- Helicobacter pylori bacteria alter the p53 stress response via Erk-HDM2 pathway
- The Functional Interplay Between the t(9;22)-Associated Fusion Proteins BCR/ABL and ABL/BCR in Philadelphia Chromosome-Positive Acute Lymphatic Leukemia
- Trial Watch: Targeting ATM–CHK2 and ATR–CHK1 pathways for anticancer therapy
- Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity
- Heterogeneous nuclear ribonucleoprotein (hnRNP) L promotes DNA damage-induced cell apoptosis by enhancing the translation of p53
- Endoplasmic Reticulum Stress Promotes Autophagy and Apoptosis and Reduces Chemotherapy Resistance in Mutant p53 Lung Cancer Cells
- The UbL-UBA Ubiquilin4 protein functions as a tumor suppressor in gastric cancer by p53-dependent and p53-independent regulation of p21
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