GGA1 Is Expressed in the Human Brain and Affects the Generation of Amyloid β-Peptide

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Summary

The data indicate that changes in the subcellular trafficking of BACE1 or other GGA1-dependent proteins contribute to changes in APP processing and Aβ generation, and GGA proteins might be involved in the pathogenesis of AD.

Type
article
Published
2006-12-06
Cited by
87
References
60
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Open access

Keywords

Constitution, Competition (biology), Context (archaeology), Investment (military), Business

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