Has the code for protein translocation been broken?

Alberto Sabio Alcutén · TIBS -Trends in Biochemical Sciences. Regular ed · 2006

Summary

It is the view that the "code" for protein translocation has not yet been deciphered and that further experiments are required for teasing apart the various energetic factors contributing toprotein translocation.

Type: article
Published: 2006-04-01
Cited by: 23
References: 27
DOI: https://doi.org/10.1016/j.tibs.2006.02.002
PubMed: https://pubmed.ncbi.nlm.nih.gov/16530414/
OpenAlex: https://openalex.org/W16530414
Semantic Scholar: https://api.semanticscholar.org/CorpusID:1196780

Keywords

Political science

References

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Cited by

MINS2: Revisiting the molecular code for transmembrane-helix recognition by the Sec61 transloconJohn Huehnergard — 2008
Sequence-based predictions of membrane-protein topology, homology and insertionAndreas Bernsel — 2008
Prédiction de la localisation des protéines membranaires : méthodes méta-heuristiques pour la détermination du potentiel d'insertion des acides aminésSami Laroum — 2011
Bacterial Physiology and Metabolism: ContentsByung Hong Kim, Geoffrey Michael Gadd — 2008
Structural determinants of lateral gate opening in the protein translocon.James C. Gumbart, Klaus Schulten — 2007
Penetration depth of surfactant peptide KL4 into membranes is determined by fatty acid saturation.Vijay C. Antharam, Douglas W. Elliott, Frank D. Mills — 2009
Hydrophobicity scales: a thermodynamic looking glass into lipid-protein interactions.Justin L. MacCallum, D. Peter Tieleman — 2011
On the energetics of translocon-assisted insertion of charged transmembrane helices into membranesAnna Rychkova, Spyridon Vicatos, Arieh Warshel — 2010
Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulationsPeter J. Bond, Mark S.P. Sansom — 2007
Membrane bending is critical for the stability of voltage sensor segments in the membraneKeith M. Callenberg, Naomi R. Latorraca, Michael Grabe — 2012
Arginine in Membranes: The Connection Between Molecular Dynamics Simulations and Translocon-Mediated Insertion ExperimentsEric V. Schow, J. Alfredo Freites, Philip Cheng — 2010
Lonely Arginine Seeks Friendly EnvironmentBenoı̂t Roux — 2007
Prediction of the translocon-mediated membrane insertion free energies of protein sequencesYungki Park, Volkhard Helms — 2008
On the thermodynamic stability of a charged arginine side chain in a transmembrane helixSudha Dorairaj, Toby W. Allen — 2007
MEMBRANE BENDING IS CRITICAL FOR ASSESSING THE THERMODYNAMIC STABILITY OF PROTEINS IN THE MEMBRANEKeith M. Callenberg — 2013
Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membraneAssaf Elazar, Jonathan J. Weinstein, Ido Biran — 2016
Decrypting protein insertion through the translocon with free-energy calculations.James C. Gumbart, Christophe Chipot — 2016
Interplay between hydrophobicity and the positive-inside rule in determining membrane-protein topologyAssaf Elazar, Jonathan Jacob Weinstein, Jaime Prilusky — 2016
potentiel d'insertion des acides amin esSami Laroum — 2014
A lipophilicity-based energy function for membrane-protein modelling and designJonathan J. Weinstein, Assaf Elazar, Sarel Jacob Fleishman — 2019

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