The size of gating charge in wild-type and mutant Shaker potassium channels.
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Summary
A more direct measurement of q in Drosophila melanogaster Shaker 29-4 potassium channels yields a q value of 12.3 e0, which can be explained by a model for channel activation in which the equilibria of voltage-dependent steps are altered in the mutant channels.
- Type
- article
- Published
- 1992-03-27
- Cited by
- 441
- References
- 18
- OpenAlex
- https://openalex.org/W2009518885
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6468774
Keywords
Shaker, Potassium channel, Gating, Voltage, Chemistry
References
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- A-type potassium channels expressed from Shaker locus cDNA.
- Hydrophobic substitution mutations in the S4 sequence alter voltage-dependent gating in Shaker K+ channels.
- Multiple products of the Drosophila Shaker gene may contribute to potassium channel diversity.
- Molecular basis of gating charge immobilization in Shaker potassium channels.
- Voltage-sensing residues in the S4 region of a mammalian K+ channel
- Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence
- Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence
- Shaker K+ channel subunits from heteromultimeric channels with novel functional properties.
- Activation of squid axon K+ channels. Ionic and gating current studies
- Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle
- Pharmacological and kinetic analysis of K channel gating currents
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- Has the code for protein translocation been broken?
- Modeling of voltage-gated ion channels
- On the estimation of cooperativity in ion channel kinetics: activation free energy and kinetic mechanism of Shaker K+ channel.
- Charged drug interactions at the inner mouth of K+ channels: Information gained from gating current studies
- A Novel K+ Channel Expressed in Carrot Roots with a Low Susceptibility Toward Metal Ions
- Handbook of ion channels
- Cysteine mutagenesis in the voltage-dependent sodium channel structural insights and implications.
- Voltage sensing in thermo-TRP channels.
- Examining cooperative gating phenomena in voltage-dependent potassium channels: taking the energetic approach.
- Consequences of Dimerization of the Voltage Gated Proton Channel
- Voltage Sensing in Membranes: From Macroscopic Currents to Molecular Motions
- Death by QT: a new safety challenge
- Lighting up life : fluorescence studies of the Shaker K⁺ channel and myosin V in action
- S3-S4 Linker Modulation of Voltage Sensor Relaxation in Voltage Gated Potassium Channels
- Discovery of an Escherichia coli channel with High voltage Dependence and Cooperativity
- Reinitiation at non-canonical start codons leads to leak expression when incorporating unnatural amino acids
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