CTLA-4 Ligation Suppresses CD28-induced NF-κB and AP-1 Activity in Mouse T Cell Blasts*

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Summary

It is proposed that the major impact of CTLA-4 ligation is inhibition of signals mediated by CD28, which regulates T cell activation by inhibiting the T cell receptor-mediated signals.

Type
dissertation
Published
1999-05-14
Cited by
98
References
38
Access
Open access

Keywords

Humanities, Geology, Art

References

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