Disruption of actin microfilaments by cytochalasin D leads to activation of p53
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Summary
The obtained data suggest that disruption of the actin microfilaments activates p53‐dependent pathways, which plays a central role in the cell's response to various stress signals.
- Type
- article
- Published
- 1998-07-03
- Cited by
- 95
- References
- 31
- OpenAlex
- https://openalex.org/W9688570
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38044707
Keywords
Humanities, Philosophy
References
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- Tumor suppressor p53 is a direct transcriptional activator of the human bax gene.
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- Differential effects of cytochalasin B and caffeine on control of DNA synthesis in normal and transformed cells
Cited by
- Optimal development of Chlamydophila psittaci in L929 fibroblast and BGM epithelial cells requires the participation of microfilaments and microtubule-motor proteins.
- Using Cytochalasins to Improve Current Chemotherapeutic Approaches
- Interaction of Staphylococcus epidermidis with abiotic and biotic surfaces: a role in bone and wound infections.
- Estudio en cultivos celulares del efecto de nanomoléculas con potencial terapéutico TESIS DOCTORAL
- Myosin light chain kinase plays a role in the regulation of epithelial cell survival
- The antitumour activities induced by pegylated liposomal cytochalasin D in murine models.
- Exposure to High-Dose Diesel Exhaust Particles Induces Intracellular Oxidative Stress and Causes Endothelial Apoptosis in Cultured In Vitro Capillary Tube Cells
- Involvement of the angiotensin II type 2 receptor in apoptosis during human fetal adrenal gland development.
- Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry
- The herbal medicine inchin-ko-to (TJ-135) induces apoptosis in cultured rat hepatic stellate cells.
- Redistribution of cytochrome c precedes the caspase-dependent formation of ultracondensed mitochondria, with a reduced inner membrane potential, in apoptotic monocytes.
- Cellular Disorganization and Extensive Apoptosis in the Developing Heart of Mice that Lack Cardiac Muscle α-Actin: Apparent Cause of Perinatal Death
- The Macaque Sperm Actin Cytoskeleton Reorganizes in Response to Osmotic Stress and Contributes to Morphological Defects and Decreased Motility1
- Rat β-glucuronidase as a reporter protein for the analysis of the plant secretory pathway
- Construction of a Reporter System for Fine Assessment of the p53 Activity in Cultured Cells
- Addition of cytochalasin D to a biocompatible oil stent coating inhibits intimal hyperplasia in a porcine coronary model
- Preparation, characterization, and anticancer efficacy of evodiamine-loaded PLGA nanoparticles
- Cytoskeletal disruption accelerates caspase-3 activation and alters the intracellular membrane reorganization in DNA damage-induced apoptosis.
- Apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase‐2
- AFM-based study of fullerenol (C60(OH)24)-induced changes of elasticity in living SMCC-7721 cells.
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