Phospholipase C-induced monocytic differentiation in a human monocytic leukemia cell line THP-1.

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Summary

The PLC-induced monocytic differentiation in THP-1 cells was inhibited by staurosporine, a potent PK-C inhibitor, further suggesting that direct activation of thePK-C is one of the metabolic events essential for monocytical differentiation.

Type
article
Published
1992-07-01
Cited by
3
References
19

Keywords

THP1 cell line, Monocytic leukemia, Acute monocytic leukemia, Cell culture, Leukemia

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