Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)
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Summary
Results indicate that THP‐1 is a leukemic cell line with distinct monocytic markers, and the ability to restore T‐lymphocyte response to Con A.
- Type
- article
- Published
- 1980-08-15
- Cited by
- 2,349
- References
- 26
- OpenAlex
- https://openalex.org/W2127310510
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43603660
Keywords
THP1 cell line, Acute monocytic leukemia, Monocytic leukemia, Cell culture, Biology
References
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- Enhancement of activity of 1alpha, 25-dihydroxyvitamin D3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, an alpha-tocopherol ester of all-trans retinoic acid.
- Cultured Human Monocytes, Granulocytes and a Monoblastoid Cell Line (THP‐1) Synthesize and Secrete Immunosuppressive Acidic Protein (a Type of α1‐Acid Glycoprotein)
- Laser Capture Microdissection as an Aid to Ultrastructural Analysis
- CD44: a new means to inhibit acute myeloid leukemia cell proliferation via p27Kip1.
- Macrophage Endocytosis of Superparamagnetic Iron Oxide Nanoparticles: Mechanisms and Comparison of Ferumoxides and Ferumoxtran-10
- 7,8-Dihydroneopterin-mediated protection of low density lipoprotein, but not human macrophages, from oxidative stress
- Specific Inhibitory Action of Anisodamine against a Staphylococcal Superantigenic Toxin, Toxic Shock Syndrome Toxin 1 (TSST-1), Leading to Down-Regulation of Cytokine Production and Blocking of TSST-1 Toxicity in Mice
- Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages.
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- Immunomodulatory activity of the lignan 7-hydroxymatairesinol potassium acetate (HMR/lignan) extracted from the heartwood of Norway spruce (Picea abies).
- Quercetin supplementation and its effect on human monocyte gene expression profiles in vivo
- Zinc and magnesium ions synergistically inhibit superoxide generation by cultured human neutrophils--a promising candidate formulation for amnioinfusion fluid.
- Regulation of Cytokine and Chemokine Expression by the Ribotoxic Stress Response Elicited by Shiga Toxin Type 1 in Human Macrophage-Like THP-1 Cells
- Dynamique de cellules sanguines dans des microécoulements
- Small Molecule Inhibition of CD40–CD154 Co-stimulatory Interaction
- Calcitonin Gene-Related Peptide Modulates the Production of Pro-Inflammatory Cytokines Associated with Periprosthetic Osteolysis by THP-1 Macrophage-Like Cells
- miR-638 Regulates Differentiation and Proliferation in Leukemic Cells by Targeting Cyclin-dependent Kinase 2*
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