Identification and characterization of essential genes in the human genome
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- Type
- article
- Published
- 2015-10-15
- Cited by
- 1,781
- References
- 51
- OpenAlex
- https://openalex.org/W1934704664
Keywords
Gene, Biology, Genome, Human genome, Genetics
References
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- Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
- Roles of Hematopoietic Transcription Factors GATA-1 and GATA-2 in the Development of Red Blood Cell Lineage
- Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies
- Systematic Analysis of Protein Pools, Isoforms, and Modifications Affecting Turnover and Subcellular Localization
- Discovery and Characterization of Super-Enhancer Associated Dependencies in Diffuse Large B-Cell Lymphoma
- Frequent mutation of histone modifying genes in non-Hodgkin lymphoma
- Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens
- Gene essentiality, gene duplicability and protein connectivity in human and mouse.
- The NCBI BioSystems database
- Changes associated with the development of resistance to imatinib (STI571) in two leukemia cell lines expressing p210 Bcr/Abl protein
- Role of duplicate genes in genetic robustness against null mutations
- The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity
- K562—A human erythroleukemic cell line
- A capture-sequencing strategy identifies IRF8, EBF1, and APRIL as novel IGH fusion partners in B-cell lymphoma.
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- Next-Generation Sequencing of Genome-Wide CRISPR Screens
- [Peroperative complications during percutaneous nephrolithotomy].
- High-resolution topographic mapping of Phobos by the HRSC on MARS-EXPRESS
- EU administrative conditionality and domestic obstacles: slow, hesitant and partial reform in post-communist Albania
- Functional genomics to uncover drug mechanism of action.
- Gene essentiality and synthetic lethality in haploid human cells
- The indispensable genome
- METHOD Open Access
- Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in Glioblastoma stem-like cells
- Leveraging Big Data to Transform Target Selection and Drug Discovery
- Structural and functional insights into enzymes of the vitamin K cycle
- Shedding Light on Synergistic Chemical Genetic Connections with Machine Learning.
- Essential Human Genes.
- The CENP-L-N complex forms a critical node in an integrated meshwork of interactions at the centromere-kinetochore interface
- Gene and Variant Annotation for Mendelian Disorders in the Era of Advanced Sequencing Technologies.
- Biophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR)
- Functional genomics: The genetic essence of human cells
- Pharmacological treats for SUMO addicts.
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- Understanding Spatial Genome Organization: Methods and Insights
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