Human cell receptors: potential drug targets to combat COVID-19
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Summary
Overall, this review focuses on the critical role of human cell receptors involved in coronavirus pathogenesis, which would likely be used in designing target-specific drugs to combat COVID-19.
- Type
- review
- Published
- 2021-05-05
- Cited by
- 24
- References
- 212
- Access
- Open access
- OpenAlex
- https://openalex.org/W3158210316
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:233741280
Keywords
Furin, Coronavirus, Angiotensin-converting enzyme 2, Proteases, Biology
References
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- Mesenchymal Stem Cells
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- The Molecular Biology of Coronaviruses
- Angiotensin-converting enzyme 2 protects from severe acute lung failure
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- Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26
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- Sequence and topology of a model intracellular membrane protein, E1 glycoprotein, from a coronavirus
- Clinical Investigations: AsthmaMatrix Metalloproteinase-9 Expression in Asthma: Effect of Asthma Severity, Allergen Challenge, and Inhaled Corticosteroids
- Genetic Characterization of Betacoronavirus Lineage C Viruses in Bats Reveals Marked Sequence Divergence in the Spike Protein of Pipistrellus Bat Coronavirus HKU5 in Japanese Pipistrelle: Implications for the Origin of the Novel Middle East Respiratory Syndrome Coronavirus
Cited by
- COVID-19 disease and malignant cancers: The impact for the furin gene expression in susceptibility to SARS-CoV-2
- Human Cell Receptors and Downstream Cascades: A Review of Molecular Aspects and Potential Therapeutic Targets against COVID-19
- OM-85 Broncho-Vaxom®, a Bacterial Lysate, Reduces SARS-CoV-2 Binding Proteins on Human Bronchial Epithelial Cells
- Pannexin-1 channel opening is critical for COVID-19 pathogenesis
- A perspective on the applications of furin inhibitors for the treatment of SARS-CoV-2
- COVID-19, Cation Dysmetabolism, Sialic Acid, CD147, ACE2, Viroporins, Hepcidin and Ferroptosis: A Possible Unifying Hypothesis
- COVID-19, liver dysfunction and pathophysiology: A conceptual discussion
- Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs
- In vitro inhibition of SARS-CoV-2 Infection by dry algae powders
- Autoimmunity and Immunodeficiency in Severe SARS-CoV-2 Infection and Prolonged COVID-19
- COVID-19 signalome: Potential therapeutic interventions
- Experimental and clinical data analysis for identification of COVID-19 resistant ACE2 mutations
- Potential treatments of COVID-19: Drug repurposing and therapeutic interventions
- Blood pH Analysis in Combination with Molecular Medical Tools in Relation to COVID-19 Symptoms
- Identifying featured indels associated with SARS-CoV-2 fitness
- Experimental and analytical pipeline for sub-genomic RNA landscape of coronavirus by Nanopore sequencer
- Predicting susceptibility to COVID-19 infection in patients on maintenance hemodialysis by cross-coupling soluble ACE2 concentration with lymphocyte count: an algorithmic approach
- Gene expression profile of immune response markers associated with long COVID and its clinical aspects in a cohort from northern Brazil.
- Soybean Trypsin Inhibitor Possesses Potency Against SARS-CoV-2 Infection by Blocking the Host Cell Surface Receptors ACE2, TMPRSS2, and CD147
- Photoactivatable DNA Conveyer Ferries Cellular Receptors to Lysosome for Collaborative Degradation in Zebrafish.
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